Department of Medical Biotechnology and Laboratory Science

Projects

Projects per year 1992 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 22 Active
• 648 Finished

Projects per year

Search results

• Active

  Investigation of the Mechanisms by Which Cellular Vapb Protein Facilitates Enterovirus Replication and the Correlation with Viral Neuropathogenicity

  Kuo, R.-L. (PI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Enterovirus 100%

• Global Profiling and Molecular Investigation of Microrna Associated with Areca Nut Induced Head-Neck Squamous Cancer

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Liu, H. (CoPI) & Shen, E. Y. L. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Malignant Neoplasm 100%
  • Areca 100%
  • microRNA 100%
  • Neck 100%

• Application of Hyperbaric Oxygen-Preconditioned-Mesenchymal Stem Cells and Its Derivatives for Treatment of Long Covid-19 Related Pulmonary Fibrosis Animal Model( II )

  Chong, K.-Y. (PI), Lin, S. S. (CoPI) & Shih, S.-R. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lung Fibrosis 100%

• Evalution of Anti-Inflammatory Effect of the Extracts Mcf-32 and Mcf-25 (Guaiacin) from the Fruit of Myristica Cagayanensis Merr on the Interaction between Human Neutrophils and Platelets

  Liao, H.-R. (PI), Chen, J. J. (CoPI), Liu, F.-C. (CoPI) & Tseng, C.-P. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Myristica 100%
  • Antiinflammatory Activity 100%

• Identification and Characterization of Coenzyme Q Synthome in the Mitochondria of Mouse Cells and Tissues

  Yen, H.-C. (PI) & Yen, T.-H. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ubiquinone 100%

• Highly Accurate Early Diagnosis, Prognosis, and Drug Screening of Parkinson'S Disease by the Development of Zeptomolar-Level Multichannel Spr Biosensor Utilizing Plasmonic Nanostructures and Deep-Red Oleds( II )

  Liu, K.-C. (PI), Chen, C. M. (CoPI) & Chiu, C.-C. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Drug Screening 100%
  • Disease 100%
  • Nanomaterial 100%

• Functional Analysis of Orf2271/Orf2272 and Theirs Roles in Regulating Virulence and Pathogenesis of Staphylococcus Aureus

  Lin, M.-H. (PI), Chang, S. C. (CoPI) & Kuo, A.-J. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Staphylococcus Aureus 100%

• Central Mechanisms of Respiratory Hypo-Sensation: Cerebral Neural Evidences Validated by 2 Respiratory Training Programs

  Chan, P.-Y. S. (PI), Hsu, A.-L. (CoPI), Lee, S. H. (CoPI), Lin, S.-M. (CoPI), Liu, C.-Y. (CoPI), Wu, C.-C. (CoPI) & Wu, Y. M. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• The Impact of Disabled-2 Protein Expression on Platelet Functions and the Bleeding Risk under the Condition of Thrombocytopenia

  Tseng, C.-P. (PI) & Wang, J. D. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombocytopenia 100%

• Impact of Posttranslational Modification of Ns2 by Ubiquitin on Influenza a Virus

  Chiu, Y.-F. (PI), Huang, C. G. (CoPI), Kuo, R.-L. (CoPI) & Yang, J. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ubiquitin 100%
  • Reproxalap 100%

• The Study of the Roles of Sphingolipid Metabolic Reprogramming in Enteroviral Replication

  Ho, H.-Y. (PI) & Chiu, C.-Y. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Sphingolipid 100%

• Unraveling the Impact of Sorting Nexin 6 on Picornavirus Infection: Investigating Unanswered Queries in Vesicular Transport and Replication Organelle Formation

  Shih, S.-R. (PI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Sorting Nexin 100%
  • Picornaviridae 100%

• Roles of Iec-Derived Micrornas and Exosomes in Enteric Rna Virus Pathogenesis

  Huang, H.-I. (PI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Virus RNA 100%
  • microRNA 100%
  • Virus Pathogenesis 100%

• Study on the Application of in Situ Synthesized Gold Nanoparticles for the Detection of Kidney Diseases

  Chang, C.-C. (PI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Kidney Disease 100%
  • Gold Nanoparticle 100%

• Effect of Rac1 on Ires-Dependent Translation in Picornavirus Infection

  Shih, S.-R. (PI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Picornavirus Infection 100%
  • Picornaviridae 100%

• Pathophysiological Functions of Mutant Pm20d1, App and Apoe Ɛ4: from Mechanisms to Therapeutic Strategies

  Chiu, C.-C. (PI), Chang, K.-H. (CoPI), Chen, Y.-C. (CoPI) & Weng, Y.-H. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Investigating the Altered Gene Expression and Neuroprotective Effect of Straight- and a Novel Branched- Medium Chain Fatty Acids in Epilepsy: Focus on Inflammasome and Mitochondrial Oxidative Stress

  Chang, B.-L. (PI), Chang, K.-H. (CoPI) & Chiu, C.-C. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Oxidative Stress 100%
  • Medium-Chain Fatty Acid 100%
  • Gene Expression 100%
  • Inflammasome 100%
  • Medium Chain Fatty Acid 100%

• Validation of the Predictive Model for Group B Streptococcus Severe Sepsis in Neonates and Investigate the Mechanisms of Virulence Factors That Cause Neonatal Sepsis

  Fu, H.-J. (PI), Chen, Y. N. (CoPI), Lin, M.-H. (CoPI), Lu, J. J. (CoPI) & Wang, H. Y. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Newborn Sepsis 100%
  • Sepsis 100%
  • Streptococcus Agalactiae 100%
  • Virulence Factor 100%

• Unraveling the Network Mechanisms in Cortical Dysplasia-Associated Epilepsy: a Comprehensive Study on Cortical Brain States and Corticothalamic Microcircuits

  Lee, C.-H. (PI), Chen, H.-H. (CoPI), Chiu, C.-C. (CoPI), Lim, S. N. (CoPI) & Wei, K.-C. C. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • And-States 100%
  • Dysplasia 100%
  • Cortical Dysplasia 100%

• Exosomal Mir-523 Derived from Human Induced Pluripotent Stem Cell Enhances Diabetic Wound Healing Using Biodegradable Core-Shell Nano/Microfibrous Plga Membranes

  Lee, C.-H. (PI), Chiu, C.-C. (CoPI) & Tsai, C. L. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Wound Healing 100%
  • Induced Pluripotent Stem Cell 100%

• The Regulatory Mechanism and Therapeutic Potential of Csf1r Pathway in Parkinson'S Disease

  Chang, K.-H. (PI), Chen, C. M. (CoPI) & Chiu, C.-C. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Disease 100%

• Systemic Profiling of Long Non-Coding Rna in Head-Neck Squamous Cancer: Clinical Implication and Functional Examination

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Chiu, C.-C. (CoPI), Huang, S.-F. (CoPI), Kang, C. J. (CoPI), Liu, H. (CoPI) & Wu, C.-C. (CoPI)

  01/08/24 → 31/07/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Malignant Neoplasm 100%
  • Neck 100%
• Finished

  Development of a Multi-Platform Detection System for Leptospirosis and Its Clinical Application( I )

  Yang, C.-W. (PI), Chang, C.-C. (CoPI) & Hsu, S. (CoPI)

  01/03/24 → 28/02/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Weil's Disease 100%
  • Leptospirosis 100%

• Research Center for Epidemic Prevention Science - Chang Gung University and Chang Gung Memorial Hospital( III )

  Tang, M.-J. (PI), Chiu, C.-H. (CoPI), Huang, P.-N. (CoPI), Shie, S. S. (CoPI) & Shih, S.-R. (CoPI)

  01/03/24 → 28/02/25

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Research Centre 100%

• Mechanism of Immune Modulation of Parabacteroides Goldsteinii Psa Capsular Polysaccharide and Its Efficacy in Amelioration of Colitis

  Lin, T.-L. (PI) & Lai, H.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Parabacteroides 100%
  • Colitis 100%
  • Polysaccharide 100%
  • Immunomodulation 100%

• Modeling Antigenicity of Sars-Cov-2 Variants for Their Association with Neutralizing Antibody Levels in Human Blood Samples

  Chen, G.-W. (PI) & Shih, S.-R. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Neutralizing Antibody 100%

• Roles of Iec-Derived Micrornas and Exosomes in Enteric Rna Virus Pathogenesis

  Huang, H.-I. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Virus RNA 100%
  • microRNA 100%
  • Virus Pathogenesis 100%
  • Exosome 100%

• Explore the Role of Il-13 Receptors in the Pathogenesis of Atopic Dermatitis and Develop the Recombinant Il-13 Receptor Based Targeted Therapy

  Shen, C.-R. (PI), Kuo, M.-L. (CoPI) & Lee, C.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Receptor 100%
  • Atopic Dermatitis 100%

• Investigation of Role of Enah-Mediated Microenvironment in Progression of Oral Cancer

  Wu, C.-C. (PI) & Chang, K.-P. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Oral Cancer 100%
  • Mouth Cancer 100%

• Development of a Predictive Model for Group B Streptococcus Strain to Cause Clinical Sepsis in Neonates and Investigate the Mechanisms of Virulence Factors That Cause Neonatal Sepsis

  Fu, H.-J. (PI), Chang, Y. C. (CoPI), Lin, M.-H. (CoPI), Lu, J. J. (CoPI) & Wang, H. Y. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Newborn Sepsis 100%
  • Sepsis 100%
  • Streptococcus Agalactiae 100%
  • Virulence Factor 100%

• Evalution of Anti-Inflammatory Effect of the Extracts Mcf-32 and Mcf-25 (Guaiacin) from the Fruit of Myristica Cagayanensis Merr on the Interaction between Human Neutrophils and Platelets

  Liao, H.-R. (PI), Chen, J. J. (CoPI), Liu, F.-C. (CoPI) & Tseng, C.-P. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Antiinflammatory Activity 100%
  • Myristica 100%

• Application of Hyperbaric Oxygen-Preconditioned-Mesenchymal Stem Cells and Its Derivatives for Treatment of Long Covid-19 Related Pulmonary Fibrosis Animal Model( I )

  Chong, K.-Y. (PI), Lin, S. S. (CoPI) & Shih, S.-R. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lung Fibrosis 100%

• The Impact of Disabled-2 Protein Expression on Platelet Functions and the Bleeding Risk under the Condition of Thrombocytopenia

  Tseng, C.-P. (PI) & Wang, J. D. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombocytopenia 100%

• Role of Acyl-Coa Synthetase Long-Chain Family Member 4 in Picornavirus Infection

  Shih, S.-R. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Picornaviridae 100%
  • Coenzyme A 100%

• The Study of the Roles of Phospholipid Metabolism in Enteroviral Infection

  Ho, H.-Y. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Enterovirus Infection 100%
  • Phospholipid 100%

• Characterization of Pdss2 and Multiple Coq Proteins and Identification of Protein Complexes Containing These Proteins in Mouse Cells and Tissues

  Yen, H.-C. (PI) & Yen, T.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Protein Complexes 100%
  • Mouse 50%

• Pathophysiological Functions of Mutant Pm20d1, App and Apoe Ɛ4: from Mechanisms to Therapeutic Strategies

  Chiu, C.-C. (PI), Chang, K.-H. (CoPI), Chen, Y.-C. (CoPI) & Weng, Y.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Exosomal Mir-523 Derived from Human Induced Pluripotent Stem Cell Enhances Diabetic Wound Healing Using Biodegradable Core-Shell Nano/Microfibrous Plga Membranes

  Lee, C.-H. (PI), Chiu, C.-C. (CoPI) & Tsai, C. L. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Wound Healing 100%
  • Induced Pluripotent Stem Cell 100%

• Global Profiling and Molecular Investigation of Microrna Associated with Areca Nut Induced Head-Neck Squamous Cancer

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Liu, H. (CoPI) & Shen, E. Y. L. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • microRNA 100%
  • Malignant Neoplasm 100%
  • Neck 100%
  • Areca 100%

• Central Mechanisms of Respiratory Hypo-Sensation: Cerebral Neural Evidences Validated by 2 Respiratory Training Programs

  Chan, P.-Y. S. (PI), Hsu, A.-L. (CoPI), Lin, S.-M. (CoPI), Liu, C.-Y. (CoPI), Wu, C.-C. (CoPI) & Wu, Y. M. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Training 100%

• A Molecule Targeting Cd28 with a High-Efficacy Therapeutic Potential for Treating Inflammatory Diseases( III )

  Kuo, M.-L. (PI), Chen, L. C. (CoPI), Huang, J.-L. (CoPI), Hwang, Y. S. (CoPI) & Shen, C.-R. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Inflammatory Disorder 100%
  • CD28 100%

• Systemic Profiling of Long Non-Coding Rna in Head-Neck Squamous Cancer: Clinical Implication and Functional Examination

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Chiu, C.-C. (CoPI), Huang, S.-F. (CoPI), Kang, C. J. (CoPI), Liu, H. (CoPI) & Wu, C.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Malignant Neoplasm 100%
  • Neck 100%

• Mechanisms Underlying the Quality Control of Secreted Proteins in Staphylococcus Aureus

  Lin, M.-H. (PI) & Chang, S. C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Staphylococcus Aureus 100%

• Investigation of the Mechanisms by Which Cellular Vapb Protein Facilitates Enterovirus Replication and the Correlation with Viral Neuropathogenicity

  Kuo, R.-L. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Enterovirus 100%

• The Regulatory Mechanism and Therapeutic Potential of Csf1r Pathway in Parkinson'S Disease

  Chang, K.-H. (PI), Chen, C. M. (CoPI) & Chiu, C.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Disease 100%

• Highly Accurate Early Diagnosis, Prognosis, and Drug Screening of Parkinson'S Disease by the Development of Zeptomolar-Level Multichannel Spr Biosensor Utilizing Plasmonic Nanostructures and Deep-Red Oleds( I )

  Liu, K.-C. (PI), Chen, C. M. (CoPI) & Chiu, C.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Drug Screening 100%
  • Disease 100%
  • Nanomaterial 100%

• An Integrated Multi-Omic Single-Cell Based Atlas to Translate Parabacteroides Goldsteinii Ameliorative Effect and Mechanism for Copd and Lung Cancer Immuno-/Metabolic- Therapy( Iv )

  Lai, H.-C. (PI), Lin, J. H. (CoPI), Lu, C. C. (CoPI) & Wu, Y. W. (CoPI)

  01/05/23 → 30/04/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lung Cancer 100%
  • Parabacteroides 100%
  • Metabolic Therapy 100%
  • Immunoglobulin 100%
  • Tamsulosin 100%

• Research Center for Epidemic Prevention Science - Chang Gung University and Chang Gung Memorial Hospital( II )

  Tang, M.-J. (PI), Chiu, C.-T. (CoPI), Chiu, C.-H. (CoPI), Chou, I. J. (CoPI), Chung, H. T. (CoPI), Hsia, S. H. (CoPI), Huang, P.-N. (CoPI), Huang, C. G. (CoPI), Lin, K. L. (CoPI), Lin, J. J. (CoPI), Shih, S.-R. (CoPI), Wong, M. C. (CoPI), Wu, C. Y. (CoPI), Yang, C.-T. (CoPI) & Yao, T.-C. (CoPI)

  01/03/23 → 02/03/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Research Centre 100%
  • Epidemics Prevention 50%

• Planning and Promotion of the Research in Microbiology, Immunology and Medical Laboratory Sciences

  Lai, H.-C. (PI)

  01/01/23 → 31/12/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Immunology and Microbiology 100%

• Exploration of Anti-Obesogenic Effect and Mechanism of Parabacteroides Goldsteinii Lipopolysaccharides

  Lai, H.-C. (PI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Parabacteroides 100%
  • Lipopolysaccharide 100%