Department of Medical Biotechnology and Laboratory Science

2024

Non-neutralizing functions in anti-SARS-CoV-2 IgG antibodies

Reinig, S. & Shih, S. R., 02 2024, In: Biomedical Journal. 47, 1, p. 100666 100666.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Overview of the Trending Enteric Viruses and Their Pathogenesis in Intestinal Epithelial Cell Infection

Chio, C. C., Chien, J. C., Chan, H. W. & Huang, H. I., 12 2024, In: Biomedicines. 12, 12, 2773.

Research output: Contribution to journal › Review article › peer-review

Open Access

Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions

Hsiung, K. C., Chiang, H. J., Reinig, S. & Shih, S. R., 12 2024, In: Vaccines. 12, 12, 1345.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Worldwide SARS-CoV-2 Omicron variant infection: Emerging sub-variants and future vaccination perspectives

Kung, Y. A., Chuang, C. H., Chen, Y. C., Yang, H. P., Li, H. C., Chen, C. L., Janapatla, R. P., Chen, C. J., Shih, S. R. & Chiu, C. H., 22 08 2024, (E-pub ahead of print) In: Journal of the Formosan Medical Association.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

2023

Gut-oriented disease modifying therapy for Parkinson's disease

Lin, C. H., Lai, H. C. & Wu, M. S., 01 2023, In: Journal of the Formosan Medical Association. 122, 1, p. 9-18 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

2022

Molecular Virology of SARS-CoV-2 and Related Coronaviruses

Kung, Y. A., Lee, K. M., Chiang, H. J., Huang, S.-Y., Wu, C. J. & Shih, S. R., 06 2022, In: Microbiology and Molecular Biology Reviews. 86, 2

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Potential to Eradicate Cancer Stemness by Targeting Cell Surface GRP78

Chen, H. Y. & Cheng, A. J., 07 2022, In: Biomolecules. 12, 7, 941.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

2021

An alternative cell therapy for cancers: Induced pluripotent stem cell (ipsc)-derived natural killer cells

Hsu, L. J., Liu, C. L., Kuo, M. L., Shen, C. N. & Shen, C. R., 10 2021, In: Biomedicines. 9, 10, 1323.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Enterovirus a71 vaccines

Li, M. L., Shih, S. R., Tolbert, B. S. & Brewer, G., 2021, In: Vaccines. 9, 3, p. 1-10 10 p., 199.

Research output: Contribution to journal › Review article › peer-review

Open Access

46 Scopus citations

Recent advancements in aptamer-based surface plasmon resonance biosensing strategies

Chang, C. C., 2021, In: Biosensors. 11, 7, 233.

Research output: Contribution to journal › Review article › peer-review

Open Access

52 Scopus citations

Role of gut microbiota in identification of novel TCM-derived active metabolites

Lin, T. L., Lu, C. C., Lai, W. F., Wu, T. S., Lu, J. J., Chen, Y. M., Tzeng, C. M., Liu, H. T., Wei, H. & Lai, H. C., 05 2021, In: Protein and Cell. 12, 5, p. 394-410 17 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

108 Scopus citations

2020

COVID-19: The first documented coronavirus pandemic in history

Liu, Y. C., Kuo, R. L. & Shih, S. R., 08 2020, In: Biomedical Journal. 43, 4, p. 328-333 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

599 Scopus citations

Enterovirus and Encephalitis

Chen, B. S., Lee, H. C., Lee, K. M., Gong, Y. N. & Shih, S. R., 20 02 2020, In: Frontiers in Microbiology. 11, 261.

Research output: Contribution to journal › Review article › peer-review

Open Access

86 Scopus citations

Genomic Insight into the Spread of Meropenem-Resistant Streptococcus pneumoniae Spain^23F-ST81, Taiwan

Chen, Y. Y., Hsieh, Y. C., Gong, Y. N., Liao, W. C., Li, S. W., Chang, I. Y. F., Lin, T. L., Huang, C. T., Chiu, C. H., Wu, T. L., Su, L. H., Li, T. H. & Huang, Y. Y., 04 2020, In: Emerging Infectious Diseases. 26, 4, p. 711-720 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Scopus citations

Host immune response against environmental nontuberculous mycobacteria and the risk populations of nontuberculous mycobacterial lung disease

Shu, C. C., Wu, M. F., Pan, S. W., Wu, T. S., Lai, H. C. & Lin, M. C., 06 2020, In: Journal of the Formosan Medical Association. 119, p. S13-S22

Research output: Contribution to journal › Review article › peer-review

Open Access

20 Scopus citations

Interfacing DNA with Gold Nanoparticles for Heavy Metal Detection

He, Z., Yin, H., Chang, C. C., Wang, G. & Liang, X., 11 2020, In: Biosensors. 10, 11, 167.

Research output: Contribution to journal › Review article › peer-review

Open Access

30 Scopus citations

Like Cures Like: Pharmacological Activity of Anti-Inflammatory Lipopolysaccharides From Gut Microbiome

Lin, T. L., Shu, C. C., Chen, Y. M., Lu, J. J., Wu, T. S., Lai, W. F., Tzeng, C. M., Lai, H. C. & Lu, C. C., 30 04 2020, In: Frontiers in Pharmacology. 11, 554.

Research output: Contribution to journal › Review article › peer-review

Open Access

94 Scopus citations

Methods for detection and study of virus-derived small RNAs produced from the intramolecular base-pairing region of the picornavirus genome

Lee, K. M., Gong, Y. N. & Shih, S. R., 01 11 2020, In: Methods: A Companion to Methods in Enzymology. 183, p. 4-12 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Simultaneous real-time detection of pregnancy-associated plasma protein-a and-a2 using a graphene oxide-based surface plasmon resonance biosensor

Fan, S. Y., Chiu, N. F., Chen, C. P., Chang, C. C. & Chen, C. Y., 2020, In: International Journal of Nanomedicine. 15, p. 2085-2094 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

2019

Antivirals and vaccines for Enterovirus A71

Lin, J. Y., Kung, Y. A. & Shih, S. R., 03 09 2019, In: Journal of Biomedical Science. 26, 1, 65.

Research output: Contribution to journal › Review article › peer-review

Open Access

71 Scopus citations

Multifaceted mechanisms of areca nuts in oral carcinogenesis: The molecular pathology from precancerous condition to malignant transformation

Li, Y. C., Cheng, A. J., Lee, L. Y., Huang, Y. C. & Chang, J. T. C., 2019, In: Journal of Cancer. 10, 17, p. 4054-4062 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

67 Scopus citations

Next generation probiotics in disease amelioration

Chang, C. J., Lin, T. L., Tsai, Y. L., Wu, T. R., Lai, W. F., Lu, C. C. & Lai, H. C., 07 2019, In: Journal of Food and Drug Analysis. 27, 3, p. 615-622 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

252 Scopus citations

Probiotics, prebiotics and amelioration of diseases

Tsai, Y. L., Lin, T. L., Chang, C. J., Wu, T. R., Lai, W. F., Lu, C. C. & Lai, H. C., 04 01 2019, In: Journal of Biomedical Science. 26, 1, 3.

Research output: Contribution to journal › Review article › peer-review

Open Access

276 Scopus citations

2018

Centennial review of influenza in Taiwan

Gong, Y. N., Kuo, R. L., Chen, G. W. & Shih, S. R., 08 2018, In: Biomedical Journal. 41, 4, p. 234-241 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

Effects of obesity on depression: A role for inflammation and the gut microbiota

Schachter, J., Martel, J., Lin, C. S., Chang, C. J., Wu, T. R., Lu, C. C., Ko, Y. F., Lai, H. C., Ojcius, D. M. & Young, J. D., 03 2018, In: Brain, Behavior, and Immunity. 69, p. 1-8 8 p.

Research output: Contribution to journal › Review article › peer-review

172 Scopus citations

2017

Anti-obesogenic and antidiabetic effects of plants and mushrooms

Martel, J., Ojcius, D. M., Chang, C. J., Lin, C. S., Lu, C. C., Ko, Y. F., Tseng, S. F., Lai, H. C. & Young, J. D., 01 03 2017, In: Nature Reviews Endocrinology. 13, 3, p. 149-160 12 p.

Research output: Contribution to journal › Review article › peer-review

226 Scopus citations

Immunomodulatory Properties of Plants and Mushrooms

Martel, J., Ko, Y. F., Ojcius, D. M., Lu, C. C., Chang, C. J., Lin, C. S., Lai, H. C. & Young, J. D., 11 2017, In: Trends in Pharmacological Sciences. 38, 11, p. 967-981 15 p.

Research output: Contribution to journal › Review article › peer-review

56 Scopus citations

Regulation Mechanisms of Viral IRES-Driven Translation

Lee, K. M., Chen, C. J. & Shih, S. R., 07 2017, In: Trends in Microbiology. 25, 7, p. 546-561 16 p.

Research output: Contribution to journal › Review article › peer-review

126 Scopus citations

2016

The adaptor protein Disabled-2: New insights into platelet biology and integrin signaling

Tsai, H. J. & Tseng, C. P., 04 10 2016, In: Thrombosis Journal. 14, 28.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

What has passed is prolog: new cellular and physiological roles of G6PD

Yang, H. C., Wu, Y. H., Liu, H. Y., Stern, A. & Chiu, D. T. Y., 02 10 2016, In: Free Radical Research. 50, 10, p. 1047-1064 18 p.

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

2015

A mitochondrial superoxide theory for oxidative stress diseases and aging

Indo, H. P., Yen, H. C., Nakanishi, I., Matsumoto, K. I., Tamura, M., Nagano, Y., Matsui, H., Gusev, O., Cornette, R., Okuda, T., Minamiyama, Y., Ichikawa, H., Suenaga, S., Oki, M., Sato, T., Ozawa, T., Clair, D. K. S. & Majima, H. J., 01 01 2015, In: Journal of Clinical Biochemistry and Nutrition. 56, 1, p. 1-7 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

267 Scopus citations

Immune checkpoint blockade therapy: The 2014 Tang prize in biopharmaceutical science

Chen, Y. S. & Shen, C. R., 01 01 2015, In: Biomedical Journal. 38, 1, p. 5-8 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

Mammalian RNA virus-derived small RNA: Biogenesis and functional activity

Weng, K. F., Hsieh, P. T., Huang, H. I. & Shih, S. R., 2015, In: Microbes and Infection. 17, 8, p. 557-563 7 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Neurotropic enterovirus infections in the central nervous system

Huang, H. I. & Shih, S. R., 24 11 2015, In: Viruses. 7, 11, p. 6029-6044 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

97 Scopus citations

Unresolved issues in the analysis of F₂-isoprostanes, F₄-neuroprostanes, isofurans, neurofurans, and F₂-dihomo-isoprostanes in body fluids and tissue using gas chromatography/negative-ion chemical-ionization mass spectrometry

Yen, H. C., Wei, H. J. & Lin, C. L., 01 07 2015, In: Free Radical Research. 49, 7, p. 861-880 20 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

2014

Avian influenza A virus infection in humans

Chen, G. W. & Shih, S. R., 01 2014, In: Biomedical Journal. 37, 1, p. 1-2 2 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Cell and tissue tropism of enterovirus 71 and other enteroviruses infections

Lin, J. Y. & Shih, S. R., 07 03 2014, In: Journal of Biomedical Science. 21, 1, 18.

Research output: Contribution to journal › Review article › peer-review

Open Access

64 Scopus citations

Impact of the gut microbiota, prebiotics, and probiotics on human health and disease

Lin, C. S., Chang, C. J., Lu, C. C., Martel, J., Ojcius, D. M., Ko, Y. F., Young, J. D. & Lai, H. C., 01 09 2014, In: Biomedical Journal. 37, 5, p. 259-268 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

115 Scopus citations

Update on enterovirus 71 infection

Huang, P. N. & Shih, S. R., 04 2014, In: Current Opinion in Virology. 5, 1, p. 98-104 7 p.

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Update on the development of enterovirus 71 vaccines

Kung, Y. A., Hung, C. T., Liu, Y. C. & Shih, S. R., 01 10 2014, In: Expert Opinion on Biological Therapy. 14, 10, p. 1455-1464 10 p.

Research output: Contribution to journal › Review article › peer-review

36 Scopus citations

2013

Nontyphoid Salmonella infection: Microbiology, clinical features, and antimicrobial therapy

Chen, H. M., Wang, Y., Su, L. H. & Chiu, C. H., 06 2013, In: Pediatrics and Neonatology. 54, 3, p. 147-152 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

208 Scopus citations

Strategies to develop antivirals against enterovirus 71

Kuo, R. L. & Shih, S. R., 2013, In: Virology Journal. 10, 28.

Research output: Contribution to journal › Review article › peer-review

Open Access

53 Scopus citations

2012

Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE

Indo, H. P., Inanami, O., Koumura, T., Suenaga, S., Yen, H. C., Kakinuma, S., Matsumoto, K. I., Nakanishi, I., St Clair, W., St Clair, D. K., Matsui, H., Cornette, R., Gusev, O., Okuda, T., Nakagawa, Y., Ozawa, T. & Majima, H. J., 08 2012, In: Free Radical Research. 46, 8, p. 1029-1043 15 p.

Research output: Contribution to journal › Review article › peer-review

49 Scopus citations

Viral and host factors that contribute to pathogenicity of enterovirus 71

Huang, H. I., Weng, K. F. & Shih, S. R., 04 2012, In: Future Microbiology. 7, 4, p. 467-479 13 p.

Research output: Contribution to journal › Review article › peer-review

62 Scopus citations

2010

N-acetylglucosamine: Production and applications

Chen, J. K., Shen, C. R. & Liu, C. L., 09 2010, In: Marine Drugs. 8, 9, p. 2493-2516 24 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

332 Scopus citations

2009

INfluenza-Associated central nervous system dysfunction in taiwanese children clinical characteristics and outcomes with and without administration of oseltamivir

Huang, Y. C., Li, W. C., Tsao, K. C., Huang, C. G., Chiu, C. H. & Lin, T. Y., 07 2009, In: Pediatric Infectious Disease Journal. 28, 7, p. 647-648 2 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

2008

Head and neck cancer in the betel quid chewing area: Recent advances in molecular carcinogenesis

Chen, Y. J., Chang, J. T. C., Liao, C. T., Wang, H. M., Yen, T. C., Chiu, C. C., Lu, Y. C., Li, H. F. & Cheng, A. J., 2008, In: Cancer Science. 99, 8, p. 1507-1514 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

263 Scopus citations

Oxidative damage markers and antioxidants in patients with acute myocardial infarction and their clinical significance

Ho, H. Y., Cheng, M. L., Chen, C. M., Gu, P. W., Wang, Y. L., Li, J. M. & Chiu, D. T. Y., 2008, In: BioFactors. 34, 2, p. 135-145 11 p.

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

2007

Glucose-6-phosphate dehydrogenase - From oxidative stress to cellular functions and degenerative diseases

Ho, H. Y., Cheng, M. L. & Chiu, D. T. Y., 06 2007, In: Redox Report. 12, 3, p. 109-118 10 p.

Research output: Contribution to journal › Review article › peer-review

130 Scopus citations

Salmonella: Clinical importance and evolution of nomenclature

Su, L. H. & Chiu, C. H., 05 2007, In: Chang Gung Medical Journal. 30, 3, p. 210-219 10 p.

Research output: Contribution to journal › Review article › peer-review

91 Scopus citations

Department of Medical Biotechnology and Laboratory Science

Research output

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