Department of Pathology

Projects

Projects per year 1992 1992 1993 1994 1995 1996 1997 2000 2002 2021 2022 2023 2024 2025

• 4 Active
• 64 Finished

Projects per year

Search results

• Finished

  Investigation of the Allosteric Activation and Immune Effector Function of Neutrophil Membrane Proteinase 3 Activity Induced by Adgrg3/Gpr97 in Health and Disease.

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Tseng, W.-Y. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Proteinase 3 100%
  • Myeloblastin 100%
  • Disease 100%

• The Role of Microrna in Endothelial Fibrotic Remodeling of Chronic Thromboembolic Pulmonary Hypertension

  Lai, Y.-J. (PI), Chang, C. J. (CoPI), Hsu, H. H. (CoPI), Huang, Y.-M. (CoPI) & Yeh, Y.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Chronic Thromboembolic Pulmonary Hypertension 100%
  • microRNA 100%

• Exploring a Simple Approach for Assessing the Mechanism of Genetic Translocation and Investigating the Clinicopathological and Molecular Significance of Chromoplexy in Sarcoma

  Huang, S.-C. (PI), Chen, T.-C. (CoPI) & Huang, C.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Gene Translocation 100%
  • Sarcoma 100%

• Investigation of the Allosteric Activation and Immune Effector Function of Neutrophil Membrane Proteinase 3 Activity Induced by Adgrg3/Gpr97 in Health and Disease.

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Tseng, W.-Y. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Proteinase 3 100%
  • Myeloblastin 100%
  • Disease 100%
  • Neutrophil 100%

• Investigating the Clinicopathologic Features of Dedifferentiated Gastric Carcinoma with Deciphering Cancer Evolution by Whole-Genome Approach

  Huang, S.-C. (PI) & Chen, T.-C. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• The Role of Microrna in Endothelial Fibrotic Remodeling of Chronic Thromboembolic Pulmonary Hypertension

  Lai, Y.-J. (PI), Chang, C. J. (CoPI), Hsu, H. H. (CoPI), Huang, Y.-M. (CoPI) & Yeh, Y.-H. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Chronic Thromboembolic Pulmonary Hypertension 100%
  • microRNA 100%

• Characterization of Recurrent Relevant Genes and Functional Pathways for Radioresistant Oral Squamous Cell Carcinoma

  Wang, C.-I. (PI), Chang, K.-P. (CoPI), Huang, Y.-M. (CoPI) & Yang, C.-Y. (CoPI)

  01/01/22 → 31/12/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Mouth Squamous Cell Carcinoma 100%

• Investigating the Clinicopathologic Features of Dedifferentiated Gastric Carcinoma with Deciphering Cancer Evolution by Whole-Genome Approach

  Huang, S.-C. (PI) & Chen, T.-C. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Investigation of the Allosteric Activation and Immune Effector Function of Neutrophil Membrane Proteinase 3 Activity Induced by Adgrg3/Gpr97 in Health and Disease.

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Tseng, W.-Y. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Proteinase 3 100%
  • Myeloblastin 100%
  • Disease 100%
  • Neutrophil 100%

• Characterization of recurrent relevant genes and functional pathways for radioresistant oral squamous cell carcinoma

  Wang, C.-I. (PI), Chang, K.-P. (CoPI), Huang, Y.-M. (CoPI) & Yang, C.-Y. (CoPI)

  01/01/21 → 31/12/21

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Mouth Squamous Cell Carcinoma 100%

• Molecular Identification of a Novel Cellular Ligand of Gpr97/Adgrg3 and Functional Characterization of Gpr97-Ligand Interaction in Human Neutrophils

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Lin, C.-Y. (CoPI)

  01/08/20 → 31/07/21

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Neutrophil Granulocyte 100%
  • G Protein Coupled Receptor 50%
  • Eicosanoid Receptor 31%
  • Receptor 31%
  • Adhesion G Protein-Coupled Receptors 25%

• Molecular Identification of a Novel Cellular Ligand of Gpr97/Adgrg3 and Functional Characterization of Gpr97-Ligand Interaction in Human Neutrophils

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Lin, C.-Y. (CoPI)

  01/08/19 → 31/07/20

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Neutrophil Granulocyte 100%

• Molecular Identification of a Novel Cellular Ligand of Gpr97/Adgrg3 and Functional Characterization of Gpr97-Ligand Interaction in Human Neutrophils

  Lin, H.-H. (PI), Chen, T.-C. (CoPI) & Lin, C.-Y. (CoPI)

  01/08/18 → 31/07/19

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Neutrophil Granulocyte 100%

• Dissecting Role of the Wnt5a in Multiple Drug Resistant Cancer Cells and Its Clinical Significance (Ii)

  Chong, K.-Y. (PI) & Chen, T.-C. (CoPI)

  01/08/17 → 31/07/18

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • Clinical Significance 100%
  • Multidrug Resistance 100%
  • Malignant Neoplasm 100%
  • Multiple Drug Resistance 87%

• Dissecting Role of the Wnt5A in Multiple Drug Resistant Cancer Cells and Its Clinical Significance (II)

  Chong, K.-Y. (PI) & Chen, T.-C. (CoPI)

  01/08/16 → 31/07/17

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • Clinical Significance 100%
  • Multidrug Resistance 100%
  • Malignant Neoplasm 100%
  • Multiple Drug Resistance 87%

• Cisplatin-Eluting Pellets for Malignant Pleural Effusion---in vivo and Animal Cancer Models

  Chao, Y.-K. (PI), Huang, Y.-M. (CoPI) & Liu, Y. H. (CoPI)

  01/08/15 → 31/07/16

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cisplatin 100%
  • Malignant Pleura Effusion 100%
  • Cancer Model 100%
  • Malignant Pleural Effusion 100%
  • Chemotherapy 71%

• Dissecting Role of the Wnt5A in Multiple Drug Resistant Cancer Cells and Its Clinical Significance (II)

  Chong, K.-Y. (PI) & Chen, T.-C. (CoPI)

  01/08/15 → 31/07/16

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • Clinical Significance 100%
  • Multidrug Resistance 100%
  • Malignant Neoplasm 100%
  • Signal Transduction 57%

• Automatic Detection and Characterization of Residual Masses in Patients with Lymphomas through Fusion of Whole-Body Diffusion-Weighted Mri on 3t and 18f-Fluorodeoxyglucose Pet/Ct

  Yen, T.-C. (PI), Huang, Y.-M. (CoPI) & Ng, S.-H. (CoPI)

  01/01/12 → 31/12/12

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Fluorodeoxyglucose F 18 100%
  • Positron Emission Tomography 100%
  • Diffusion MRI 62%
  • Biological Marker 37%
  • Fluorodeoxyglucose 37%

• Establishment of a Personalized Medicine in Cholangocarcinoma Patients Based on Tissue Microarray

  Yeh, T.-S. (PI) & Chen, T.-C. (CoPI)

  01/08/11 → 31/10/12

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Personalized Medicine 100%
  • Tissue Microarray 100%
  • Cholangiocarcinoma 100%
  • Small Interfering RNA 11%
  • Implant 11%

• Utility of Altered Peptide Ligands to Protect against Allergic Asthma

  Chen, T.-C. (PI) & Wu, K. F. (CoPI)

  01/08/11 → 31/07/12

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allergic Asthma 100%
  • Allergen 100%
  • Immunoglobulin E 100%
  • Regulatory T Cell 100%
  • Respiratory Tract Inflammation 66%

• Establishment of a Personalized Medicine in Cholangocarcinoma Patients Based on Tissue Microarray

  Yeh, T.-S. (PI) & Chen, T.-C. (CoPI)

  01/08/10 → 31/07/11

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Tissue Microarray 100%
  • Personalized Medicine 100%
  • Cholangiocarcinoma 100%
  • Flank 18%
  • Malignant Neoplasm 18%

• Utility of Altered Peptide Ligands to Protect against Allergic Asthma

  Chen, T.-C. (PI) & Wu, K. F. (CoPI)

  01/08/10 → 31/07/11

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allergic Asthma 100%
  • Respiratory Tract Inflammation 100%
  • Immunoglobulin E 100%
  • Regulatory T Cell 100%
  • Immunotherapy 75%

• Search for Quantitative PCR Markers on Diallelic Short Insertion/Deletion Polymorphism for Transplant Chimerism--Establishing Data Base and Evaluating Clinical Impact

  Sun, C.-F. (PI) & Chen, D. P. (CoPI)

  01/08/09 → 31/07/10

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Indel 100%
  • Real-Time Polymerase Chain Reaction 100%
  • Chimera 50%

• Search for Quantitative PCR Markers on Diallelic Short Insertion/Deletion Polymorphism for Transplant Chimerism---Establishing Data Base and Evaluating Clinical Impact

  Sun, C.-F. (PI) & Chen, D. P. (CoPI)

  01/08/08 → 31/07/09

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Real-Time Polymerase Chain Reaction 100%
  • Transplant Procedure 100%
  • Indel Mutation 100%
  • Chimera 100%
  • Engraftment 50%

• Investigation into the Mechanisms of Transplantation Toleterance Induced by Peptide Vaccines

  Chen, T.-C. (PI), Lin, H.-H. (CoPI) & Wu, K. F. (CoPI)

  01/08/08 → 31/07/09

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • CD4 100%
  • Peptide Vaccine 100%
  • Skin Graft 100%
  • Graft Rejection 75%
  • C57BL 6 Mouse 66%

• Search for Quantitative Pcr Markers on Diallelic Short Insertion/Deletion Polymorphism for Transplant Chimerism---Establishing Data Base and Evaluating Clinical Impact

  Sun, C.-F. (PI) & Chen, D. P. (CoPI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Indel 100%
  • Chimera 50%

• Investigation into the Mechanisms of Transplantation Toleterance Induced by Peptide Vaccines

  Chen, T.-C. (PI), Lin, H.-H. (CoPI) & Wu, K. F. (CoPI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Vaccine Peptide 100%
  • Peptide Vaccine 100%

• Study of Mechanism for Weak Expression of Rare ABO Alleles (III)

  Sun, C.-F. (PI), Chen, D. P. (CoPI) & Tseng, C.-P. (CoPI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allele 100%

• Investigation into the Mechanisms of Transplantation Toleterance Induced by Peptide Vaccines

  Chen, T.-C. (PI), Lin, H.-H. (CoPI) & Wu, K. F. (CoPI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Vaccine Peptide 100%
  • Peptide Vaccine 100%

• Study of the Cells Mediating Infectious Tolerance

  Chen, T.-C. (PI) & Wu, K. F. (CoPI)

  01/08/05 → 31/07/06

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Study of Mechanism for Weak Expression of Rare ABO Alleles (II)

  Sun, C.-F. (PI), Chen, D. P. (CoPI) & Tseng, C.-P. (CoPI)

  01/08/05 → 31/07/06

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allele 100%

• Study of Mechanism for Weak Expression of Rare ABO Alleles (I)

  Sun, C.-F. (PI), Chen, D. P. (CoPI) & Tseng, C.-P. (CoPI)

  01/08/04 → 31/07/05

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allele 100%

• Dertermination of Prevalent RHD Gene Allels and Study of RHD Gene Expression (II)

  Sun, C.-F. (PI)

  01/08/03 → 31/07/04

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • RHD (Gene) 100%
  • Gene Expression 100%

• 解剖、病理及法醫學門規劃研究推動計畫

  Kuo, T.-T. (PI)

  01/01/03 → 31/12/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Cutaneous Malignant Lymphomas---Pathologic, Immunohistochemical and Molecular Studies (III)

  Kuo, T.-T. (PI)

  01/08/02 → 31/07/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lymphoma 100%

• Human Papillomavirus DNA Analysis of Cytology-Negative Pap Smears Obtained within 5 Years of the Diagnosis of in-situ and Invasive Cervical Cancer

  Chen, W.-J. (PI)

  01/08/02 → 31/07/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cytotechnology 100%
  • Wart Virus 100%
  • DNA Determination 100%
  • Papanicolaou Stain 100%
  • Cervical Cancer 100%

• Dertermination of Prevalent RHD Gene Allels and Study of RHD Gene Expression (I)

  Sun, C.-F. (PI)

  01/08/02 → 31/07/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • RHD (Gene) 100%
  • Gene Expression 100%
  • Rheumatic Heart Disease 100%

• 解剖、病理及法醫學門規劃研究推動計劃

  Kuo, T.-T. (PI)

  01/01/02 → 31/12/02

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

• Cutaneous Malignant Lymphomas---Pathologic, Immunohistochemical, and Molecular Studies (II)

  Kuo, T.-T. (PI)

  01/08/01 → 30/11/02

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lymphoma 100%

• Cutaneous Malignant Lymphomas---Pathologic, Immunohistochemical, and Molecular Studies (I)

  Kuo, T.-T. (PI)

  01/08/00 → 30/11/01

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lymphoma 100%

• Correlation of Th2 Cells and Immunomodulation in Gastric Cancer Patients---Using Postoperative Infection and Survival as Indicators

  Sun, C.-F. (PI)

  01/08/00 → 31/12/01

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Immunomodulation 100%
  • Stomach Cancer 100%
  • Postoperative Infection 100%

• Expression of MIB-1, bcl-2 and p53 by Immunohistochemical Technique and Analysis of DNA Content, S-Phase Fraction by Flow Cytometry of Medullary Carcinoma with Clinical Correlation

  Chen, W.-J. (PI)

  01/08/00 → 31/01/02

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Flow Cytometry 100%
  • Medullary Carcinoma 100%
  • Protein P53 100%

• The Role of TH2 Cells in Transfusion-Induced Immunomodulation

  Sun, C.-F. (PI)

  01/08/99 → 31/07/00

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Immunomodulation 100%

• Cytokeratin Profile and Related Antigenic Expression of Thymic Carcinoma and Immunohistochemical Alteration in Thymoma Undergoing Malignant Transformation into Thymic Carcinoma

  Kuo, T.-T. (PI)

  01/08/98 → 31/07/99

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thymic Carcinoma 100%
  • Malignant Transformation 100%
  • Cytokeratin 100%
  • Thymoma 50%
  • Thymus Cancer 50%

• Expression of Thrombomodulin in Cervical Cancers and Its Relationship to Tumor Angiogenesis and Metastasis

  Chen, W.-J. (PI)

  01/08/97 → 31/07/98

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombomodulin 100%
  • Uterine Cervix Cancer 100%
  • Neoplasm 100%

• Molecular Study of RHD Gene---Expression Mechanism of RHD Gene with DEL Chinese as Studying Model

  Sun, C.-F. (PI)

  01/08/97 → 31/07/98

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Rheumatic Heart Disease 100%

• Study of Neuroendocrine Differentiation in Thymic Carcinoma

  Kuo, T.-T. (PI)

  01/08/97 → 31/07/98

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thymic Carcinoma 100%
  • Neuroendocrine Differentiation 100%
  • Carcinoma 100%

• Characterization of the Cytokeratin Profiles of Normal Thymus and Thymic Epithelial Tumors

  Kuo, T.-T. (PI)

  01/08/96 → 31/07/97

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Epithelium Tumor 100%
  • Cytokeratin 100%

• PCR-SSP with High Resolution Typings and Direct Sequencing of HLA DRB1/3/4/5, DQB1 and DPB1 Alleles

  Sun, C.-F. (PI)

  01/08/96 → 31/07/97

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Allele 100%
  • HLA-DRB1 100%
  • Polymerase Chain Reaction 50%

• Tumor Angiogenesis and p53 Expression in Stage I and II Cervical Cancers

  Chen, W.-J. (PI)

  01/08/96 → 31/07/97

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Uterine Cervix Cancer 100%
  • Neoplasm 100%
  • Protein P53 100%