Graduate Institute of Biomedical Sciences

Active

Role of Core Fucosylation of Secreted Protein Acidic and Rich in Cysteine (Sparc) in Chronic Obstructive Pulmonary Disease (Copd): Impact of Hypoxia and Polycyclic Aromatic Hydrocarbons

Wang, C.-H. (PI) & Yu, J. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Retrospective Validation of Prognostic and Therapeutic Biomarkers via Multiple Reaction Monitoring Proteomic Approach Applied in Ffpe Samples.

Hsiao, Y.-C. (PI), Chang, K.-P. (CoPI) & Yu, J.-S. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Investigating Cellular Processes and Molecular Regulation Governed by Akt-Related Chemicals to Promote Spinal Cord Recovery after Injury

Cheng, Y.-C. (PI), Chen, Y. C. (CoPI) & Huang, Y. C. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Convection Enhanced Delivery with Pd-L1 Targeted Icg/Resiquimod-Loaded Liposomes Triggered by Laser Interstitial Thermal Therapy for Enhanced Glioma in Situ Vaccination.

Lu, Y.-J. (PI), Chen, J.-P. (CoPI), Wei, K.-C. C. (CoPI) & Yu, A.-T. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Exploring Peak Picking Challenges in Mass Spectrometry Data, Developing Automated Peak Picking Models, and Establishing Evaluation Strategy

Lee, C.-C. (PI), Hsiao, Y.-C. (CoPI) & Yeh, Y. M. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Comprehensively Assess the Impact of Globo H on Anaplastic Thyroid Carcinoma as a Potential Therapeutic Target

Wu, C.-E. (PI), Hung, T. H. (CoPI), Yeh, C. N. (CoPI) & Yu, A.-T. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Establishment of Intrahepatic Cholangiocarcinoma Mice Model to Explore Immune Microenvironment and Anti-Pd1 Treatment Biomarkers

Huang, W.-K. (PI), Hung, T. H. (CoPI), Yeh, C. N. (CoPI) & Yu, A.-T. (CoPI)

01/08/24 → 31/07/25

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Finished

Development of Novel Allogeneic Cell Therapies( III )

Yu, J. (PI), Chang, H. (CoPI), Hung, J. T. (CoPI), Jaing, T.-H. (CoPI), Lai, C.-H. (CoPI), Tang, Y. H. (CoPI), Yeh, C. N. (CoPI) & Yu, A.-T. (CoPI)

01/05/24 → 30/04/25

Project: National Science and Technology Council › National Science and Technology Council Grants Research

Discovery and Verification of Extracellular Vesicular (Ev)-Associated Proteins as Novel Plasma Biomarkers for Pancreatic Cancer Detection (Ii)

Yu, J.-S. (PI), Chu, L. J. (CoPI) & Yeh, T.-S. (CoPI)

01/11/23 → 31/10/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Convection Enhanced Delivery with Pd-L1 Targeted Icg/Resiquimod-Loaded Liposomes Triggered by Laser Interstitial Thermal Therapy for Enhanced Glioma in Situ Vaccination.

Lu, Y.-J. (PI), Chen, J.-P. (CoPI), Wei, K.-C. C. (CoPI) & Yu, A.-T. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Significance of Prelimbic-Nucleus Accumbens Projection and Mirna-199a-3p in Stress-Induced Methamphetamine Reinstatement( III )

Chen, J.-C. (PI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Electrochemical Biosensors Using Screen Printed Carbon Electrodes and Magnetic Carbon Nanomaterials for Fast Virus Detection and Diagnosis(Iii)

Liu, C.-H. (PI), Hsiao, Y.-C. (CoPI) & Wu, W. C. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Exploring the Molecular Mechanism of Oral Potentially Malignant Diseases (Opmds) Transforming into Oral Cancer Using Spatial Omics Technologies

Chu, L. J. (PI), Chang, K.-P. (CoPI), Huang, C.-C. (CoPI) & Yu, J.-S. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Role of Core Fucosylation of Secreted Protein Acidic and Rich in Cysteine (Sparc) in Chronic Obstructive Pulmonary Disease (Copd): Impact of Hypoxia and Polycyclic Aromatic Hydrocarbons

Wang, C.-H. (PI) & Yu, J. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Building a One-Stop Platform Applying Deep Neural Networks to Optimize Signature Peptide Selections for Assay Designs of Mrm-Based Absolute Quantifications in Targeted Proteomics

Yang, C. (PI), Hsiao, Y.-C. (CoPI) & Yu, J.-S. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Clinical Significance of Thyroid Hormone-Regulated Non-Coding Rnas( III )

Lin, K.-H. (PI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Investigating the Role of Pla2g6/Pla2g6 in Neural Crest-Derived Melanocyte Development and Melanomagenesis

Cheng, Y.-C. (PI), Huang, Y. C. (CoPI) & Yeh, T. H. (CoPI)

01/08/23 → 31/07/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Development of Novel Allogeneic Cell Therapies( II )

Yu, J. (PI), Chang, H. (CoPI), Hung, J. T. (CoPI), Jaing, T.-H. (CoPI), Lai, C.-H. (CoPI), Tang, Y. H. (CoPI), Yeh, C. N. (CoPI) & Yu, A.-T. (CoPI)

01/05/23 → 30/04/24

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Studing the Mechanisms of Oral Cancer Progression and Identifying the Potential Biomarkers of Detection and Treatment for Oscc by Abrasion Stress for Cells

Wu, C.-S. (PI), Chang, K.-P. (CoPI) & Hsiao, Y.-C. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Convection Enhanced Delivery with Pd-L1 Targeted Icg/Resiquimod-Loaded Liposomes Triggered by Laser Interstitial Thermal Therapy for Enhanced Glioma in Situ Vaccination.

Lu, Y.-J. (PI), Chen, J.-P. (CoPI), Wei, K.-C. C. (CoPI) & Yu, A.-T. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Significance of Prelimbic-Nucleus Accumbens Projection and Mirna-199a-3p in Stress-Induced Methamphetamine Reinstatement( II )

Chen, J.-C. (PI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Efficacy of Anti-Aging Ganoderma Lucidum Compounds against Parkinson'S Disease

Peng, H.-H. (PI), Chen, J.-C. (CoPI) & Hwang, T.-L. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Clinical Significance of Thyroid Hormone-Regulated Non-Coding Rnas( II )

Lin, K.-H. (PI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Investigating the Role of Pla2g6/Pla2g6 in Neural Crest-Derived Melanocyte Development and Melanomagenesis

Cheng, Y.-C. (PI), Huang, Y. C. (CoPI) & Yeh, T. H. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Examination of Selected Evs Membrane Proteins as Novel Salivary Biomarkers for Disease Detection/Monitoring and Reveal of Evs-Mediated Mechanisms for Cancer Progression in Oscc

Chu, L. J. (PI) & Chang, K.-P. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Role of Core Fucosylation of Secreted Protein Acidic and Rich in Cysteine (Sparc) in Chronic Obstructive Pulmonary Disease (Copd): Impact of Hypoxia and Polycyclic Aromatic Hydrocarbons

Wang, C.-H. (PI) & Yu, J. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Developing a Deep Reinforcement Learning Framework and Training Intelligent Agents to Perform High-Quality Data Analysis of Multiple Reaction Monitoring Datasets for Targeted Mass Spectrometry

Yang, C. (PI), Hsiao, Y.-C. (CoPI), Tsai, M.-H. (CoPI) & Yu, J.-S. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Comprehensive Evaluation of Puf-A as a Possible Therapeutic Target Associated with Tumorigenesis in Intrahepatic Cholangiocarcinoma

Wu, C.-E. (PI), Yeh, C. N. (CoPI) & Yu, J. (CoPI)

01/08/22 → 31/07/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Discovery and Verification of Extracellular Vesicle (Ev)-Associated Proteins as Novel Plasma Biomarkers for Pancreatic Cancer Detection

Yu, J.-S. (PI), Chu, L. J. (CoPI) & Yeh, T.-S. (CoPI)

01/06/22 → 31/05/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Development of Novel Allogeneic Cell Therapies( I )

Yu, J. (PI), Chang, H. (CoPI), Hung, J. T. (CoPI), Jaing, T.-H. (CoPI), Lai, C.-H. (CoPI), Tang, Y. H. (CoPI), Yeh, C. N. (CoPI) & Yu, A.-T. (CoPI)

01/05/22 → 30/04/23

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Planning and Promotion of the Research in Morphological Medicine and Physiology

Chen, J.-C. (PI)

01/01/22 → 31/12/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Investigation for Radiotherapy and Crispr Gene Editing to Activate Immunity and Apply It to Tumor Nuclear Imaging Platform

Hsiao, Y.-C. (PI) & Cheng, C.-C. (CoPI)

01/01/22 → 31/12/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Evaluate the Relationship between Α-Synuclein Expression and Dopamine Neuron Degeneration on a Pffs Injected Pd Animal Model

Weng, C.-C. (PI) & Chen, J.-C. (CoPI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Significance of Prelimbic-Nucleus Accumbens Projection and Mirna-199a-3p in Stress-Induced Methamphetamine Reinstatement( I )

Chen, J.-C. (PI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Comprehensive Evaluation of Puf-A as a Possible Therapeutic Target Associated with Tumorigenesis in Intrahepatic Cholangiocarcinoma

Wu, C.-E. (PI), Yeh, C. N. (CoPI) & Yu, J. (CoPI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Clinical Significance of Thyroid Hormone-Regulated Non-Coding Rnas( I )

Lin, K.-H. (PI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Development of Novel Ctp-Conjugated Pseudomonas Exotoxin for Cancer Therapy

Yu, J. (PI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Investigating the Role of Pla2g6/Pla2g6 in Neural Crest-Derived Melanocyte Development and Melanomagenesis

Cheng, Y.-C. (PI), Huang, Y. C. (CoPI) & Yeh, T. H. (CoPI)

01/08/21 → 31/07/22

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Planning and promotion of the research in morphological medicine and physiology

Chen, J.-C. (PI)

01/01/21 → 31/12/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Biological Significance of Hormone-Regulated Non-Coding Rnas

Lin, K.-H. (PI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Exploration of Exosomal Membrane Proteins as Novel Salivary Biomarkers for Early Detection/Disease Monitoring and Reveal of Salivary Exosome-Mediated Mechanisms for Cancer Progression in Oscc

Chu, L. J. (PI), Chang, K.-P. (CoPI) & Yu, J.-S. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Chemical Isotope Labeling Quantitative Metabolomics for Salivary Profiling of the Amine/Phenol/Hydroxyl Submetabolome and Investigating the Clinical Applications in Oral Cancer( II )

Chen, Y.-T. (PI), Chang, K.-P. (CoPI), Chu, L. J. (CoPI) & Yu, J.-S. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Preclinical Evaluation of Convection-Enhanced Delivery of Gd2directed Thermosensitive Magnetic Immunoliposomes Carrying Irinotecan and Demethylase Inhibitors to Treat Pediatric Diffuse Intrinsic Pontine Glioma(2))(3).

Lu, Y.-J. (PI), Chen, J.-P. (CoPI), Hung, J. T. (CoPI), Wei, K.-C. C. (CoPI) & Yu, A.-T. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Role of Prefrontal Glutamate to Ventral Tegmental Area Gaba Neural Circuitry on Extinction of Methamphetamine Addiction

Chen, J.-C. (PI) & Huang, R.-C. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Targeted Mass Spectrometry-Based, Prospective Verification of Protein Biomarkers in Dry Saliva Spots for Monitoring the Recurrence of Oral Cancer and Malignant Transformation of Oral Precancer Lesions

Hsiao, Y.-C. (PI), Chang, K.-P. (CoPI) & Yu, J.-S. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Metabolic Reprogramming in Arrhythmogenic Right Ventricular Cardiomyopathy: a Human Ips-Based Multisystem Approach

Yeh, Y.-H. (PI), Cheng, M.-L. (CoPI), Hsu, L.-A. (CoPI) & Yu, J. (CoPI)

01/08/20 → 31/07/21

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Planning and Promotion of the Research in Morphological Medicine and Physiology

Chen, J.-C. (PI)

01/01/20 → 31/12/20

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Assessment of Mass Spectrometry Waveform Peak Peaking Problem, Deep Learning Model Construction, Re-Training and Associated Applications Developing

Lee, C.-C. (PI) & Chu, L. J. (CoPI)

01/08/19 → 31/07/20

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Mechanisms and Significance of Thyroid Hormone Suppress Regulatory Rna Expression in Cancer

Lin, K.-H. (PI)

01/08/19 → 31/07/20

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

The Biological Significance of the Dysregulated Linc1488 Gene in Human Cancers

Lin, K.-H. (PI)

01/08/19 → 31/07/20

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Graduate Institute of Biomedical Sciences

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