Graduate Institute of Clinical Medical Sciences

Projects

Projects per year 1992 2004 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 20 Active
• 397 Finished

Projects per year

Search results

• Finished

  Autoantibodies against Interferons Underlying Infectious Diseases

  Ku, C.-L. (PI), Lei, W. T. (CoPI) & Tu, K. H. (CoPI)

  01/01/24 → 31/12/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Autoantibodies 100%
  • Interferon 100%
  • Infection 100%

• Autologous Transplantation of Functional Epithelial Cell Sheets in Tracheal Tissue Engineering

  Tsao, C.-K. (PI) & Huang, S.-F. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Autotransplantation 100%
  • Tissue Engineering 100%

• Molecular Analysis of Norovirus-Host Cell Interaction

  Chang, P.-J. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Norovirus 100%

• Intelligent Case Manage Platform to Improve Self-Management and Health-Related Outcome among Liver Transplant Recipients: Connection with Artificial Intelligence and Deep Learning

  Weng, L.-C. (PI), Huang, H.-L. (CoPI), Lee, W.-C. (CoPI), Shieh, W.-Y. (CoPI), Tsai, Y.-H. (CoPI) & Tsai, P. C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Self Care 100%
  • Liver Graft 100%
  • Self-Management 100%
  • Artificial Intelligence 50%

• Genomic Alterations in Young Aged Head and Neck Cancer: from Phenotypic Variability to Genetic Susceptibility

  Huang, S.-F. (PI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Genetic Susceptibility 100%
  • Genomics 50%

• Epitopes of Anti-Gm-Csf Autoantibody and Their Corresponding Downstream Signal Regulation

  Wang, S.-Y. (PI) & Ku, C.-L. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Autoantibodies 100%
  • Epitope 100%

• The Role and Therapeutic Potential of Macropinocytosis and Β2-Adrenergic Receptor Signaling in Wild-Type and Mutated Kras Colorectal Cancer Cells

  Shi, C.-S. (PI), Chin, C. C. (CoPI) & Kuan, F. C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Adrenergic Receptor 100%
  • Colorectal Cancer 50%
  • Colorectal Carcinoma 50%

• Limination of the Anticytokine Autoantibody Productizing B Cells by Reengineering Chimeric Autoantibody Receptor T Cells

  Ku, C.-L. (PI) & Tu, K. H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Autoantibodies 100%
  • T Cell Receptor 100%
  • B Cell 100%

• Genetic Biomarkers of Child Language Development in Taiwan: an Identification and Validation Study

  Chen, C.-L. (PI), Chang, C. J. (CoPI), Chung, W.-H. (CoPI), Lee, Y.-S. (CoPI), Lin, K. L. (CoPI), Lin, J. L. (CoPI) & Lu, J. J. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Child Language 100%
  • Biological Marker 100%
  • Language Development 100%
  • Genetics 100%

• The Response of Incretin Therapy through the Regulation of Vtrna2-1 Gene

  Lin, C.-H. (PI), Huang, Y. Y. (CoPI) & Tsai, C.-N. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Incretin 100%

• To Study Sox4 Mediated De Novo Serine-Ceramide Synthesis Pathway and Its Impact on Macrophage Polarization in Hepatocellular Carcinoma Cells

  Tsai, C.-N. (PI), Lee, Y.-S. (CoPI) & Yu, M. C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ceramide 100%
  • Serine 100%
  • Macrophage 100%
  • Liver Cell Carcinoma 100%

• Dysregulation of Dna Damage Response by Ubiquitinated Androgen Receptor Aggregates: Mechanisms and Therapeutic Applications of Kennedy’S Disease

  Kang, H.-Y. (PI), Chang, K.-H. (CoPI), Chuang, S. H. (CoPI) & Yang, J. L. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Disease 100%
  • Androgen Receptor 100%

• Characterization of the Impact of Infection-Mediated Sr Protein Phospho-Regulation on Viral Replication

  Lee, K.-M. (PI), Gong, Y.-N. (CoPI) & Huang, Y.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Phosphoprotein 100%
  • Virus Replication 100%

• The Role of Aryl Hydrocarbon Receptor in the Pathogenesis of Atrial Remodeling and Fibrillation( II )

  Chen, W.-J. (PI) & Chang, G.-J. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Heart Atrium Remodeling 100%
  • Aromatic Hydrocarbon Receptor 100%
  • Atrial Fibrillation 100%

• Interaction between Aldh2, Ho-1 and Ferroptosis in Atrial Fibrillation

  Hsu, L.-A. (PI), Chang, G.-J. (CoPI) & Yeh, Y.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ferroptosis 100%
  • Atrial Fibrillation 100%

• Differential Antiarrhythmic Effect and Electrophsiological Mechanisms of an Analogue of Istaroxime Metabolite in Healthy and Cardiac Hypertrophic Guinea Pigs

  Chang, G.-J. (PI) & Chen, W.-J. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Guinea Pig 100%
  • Antiarrhythmic Agent 100%
  • Istaroxime 100%

• A Snakemake Workflow Vi Stualization Platform for Biomedical Imaging and Informatics

  Wan, S.-Y. (PI), Fu, C. H. (CoPI) & Lee, T.-J. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Biomedical Imaging 100%

• The Use of Chinese Herbal Medicine to Regulate Lipid Metabolism for Non-Alcoholic Fatty Liver Disease (Nafld): Big Data and Network Pharmacology with Experiment Validation.

  Chen, H.-Y. (PI), Huang, Y. T. (CoPI), Pang, J.-H. S. (CoPI) & Wu, Y.-H. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Network Pharmacology 100%
  • Nonalcoholic Fatty Liver 100%

• Systemic Profiling of Long Non-Coding Rna in Head-Neck Squamous Cancer: Clinical Implication and Functional Examination

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Chiu, C.-C. (CoPI), Huang, S.-F. (CoPI), Kang, C. J. (CoPI), Liu, H. (CoPI) & Wu, C.-C. (CoPI)

  01/08/23 → 31/07/24

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Malignant Neoplasm 100%
  • Neck 100%

• Autoantibodies against Interferons Underlying Infectious Diseases

  Ku, C.-L. (PI), Lei, W. T. (CoPI) & Tu, K. H. (CoPI)

  01/01/23 → 31/12/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Autoantibodies 100%
  • Interferon 100%
  • Infection 100%

• Study of the Coordinated Assembly of Kshv Lytic Dna Replication Proteins

  Chang, P.-J. (PI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Replication Protein 100%

• The Role of Aryl Hydrocarbon Receptor in the Pathogenesis of Atrial Remodeling and Fibrillation( I )

  Chen, W.-J. (PI) & Chang, G.-J. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Atrial Fibrillation 100%
  • Heart Atrium Remodeling 100%
  • Aromatic Hydrocarbon Receptor 100%

• The Anti-Type I Interferon Autoantibodies in Humans Predispose to Infectious Diseases

  Ku, C.-L. (PI), Kuo, C.-Y. (CoPI) & Tu, K. H. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Interferon Type I 100%
  • Autoantibodies 100%
  • Infection 100%
  • interferon 100%

• Dysregulation of Dna Damage Response by Ubiquitinated Androgen Receptor Aggregates: Mechanisms and Therapeutic Applications of Kennedy’S Disease

  Kang, H.-Y. (PI), Chang, K.-H. (CoPI), Chuang, S. H. (CoPI) & Yang, J. L. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Androgen Receptor 100%
  • Disease 50%
  • Diseases 50%

• Investigating the Molecular Mechanism of Rev-Erb in Energy Homeostasis and Metabolic Disorder

  Yang, M.-Y. (PI), Lin, H.Y.-H. (CoPI) & Yang, C. H. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Metabolic Disorder 100%

• To Study Interaction between Sox4 and Nrf2-Keap1-Are Signaling in Hepatocellular Carcinoma and Its Clinical Impact

  Tsai, C.-N. (PI) & Yu, M. C. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Interaction Study 100%
  • Transcription Factor Nrf2 100%

• Systemic Profiling of Long Non-Coding Rna in Head-Neck Squamous Cancer: Clinical Implication and Functional Examination

  Cheng, A.-J. (PI), Chang, J.T.-C. (CoPI), Chiu, C.-C. (CoPI), Huang, S.-F. (CoPI), Kang, C. J. (CoPI), Liu, H. (CoPI) & Wu, C.-C. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Malignant Neoplasm 100%
  • Neck 100%

• Genomic Alterations in Young Aged Head and Neck Cancer: from Phenotypic Variability to Genetic Susceptibility

  Huang, S.-F. (PI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Genetic Susceptibility 100%
  • Genomics 50%

• Intelligent Case Manage Platform to Improve Self-Management and Health-Related Outcome among Liver Transplant Recipients: Connection with Artificial Intelligence and Deep Learning

  Weng, L.-C. (PI), Huang, H.-L. (CoPI), Lee, W.-C. (CoPI), Shieh, W.-Y. (CoPI), Tsai, Y.-H. (CoPI) & Tsai, P. C. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Self Care 100%
  • Liver Graft 100%
  • Self-Management 100%
  • Artificial Intelligence 50%

• The Use of Chinese Herbal Medicine to Regulate Lipid Metabolism for Non-Alcoholic Fatty Liver Disease (Nafld): Big Data and Network Pharmacology with Experiment Validation.

  Chen, H.-Y. (PI), Huang, Y. T. (CoPI), Pang, J.-H. S. (CoPI) & Wu, Y.-H. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Network Pharmacology 100%
  • Nonalcoholic Fatty Liver 100%

• Genetic Biomarkers of Child Language Development in Taiwan: an Identification and Validation Study

  Chen, C.-L. (PI), Chang, C. J. (CoPI), Chung, W.-H. (CoPI), Lee, Y.-S. (CoPI), Lin, K. L. (CoPI), Lin, J. L. (CoPI) & Lu, J. J. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Language Development 100%
  • Child Language 100%
  • Biological Marker 100%
  • Genetics 100%

• Differentially Methylated Regions (Dmrs) Regulates Glp-1 Analogue in Glucose Control and Clinical Response

  Lin, C.-H. (PI), Huang, Y. Y. (CoPI), Lee, Y.-S. (CoPI) & Tsai, C.-N. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Differentially Methylated Regions 100%

• Merging Nhird and Basic Study to Create the Novel Screening Platform of Anti-Prostate Cancer Herbs-The Role and Mechanism of Astragalus Polysaccharides on Pd-1/Pd-L1 Immunotherapy and Ferroptosis of Prostate Cancer

  Wu, C.-Y. (PI), Kang, H.-Y. (CoPI) & Yang, Y.-H. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ferroptosis 100%
  • Astragalus 100%
  • Prostate Cancer 100%
  • Immunotherapy 100%
  • Polysaccharide 100%

• Identifying Type 2 Inflammation Chronic Rhinosinusitis with Nasal Polyps

  Huang, C.-C. (PI), Chang, P. H. (CoPI), Huang, C. C. (CoPI), Lee, T.-J. (CoPI) & Wu, P.-W. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Inflammation 100%
  • Chronic Rhinosinusitis 100%
  • Nose Polyp 100%

• Mechanistic Strategies of Vpc-Induced Cardiomyopathy Originating from Right Ventricular Outflow Tract

  Lin, Y.-S. (PI), Chang, P.-J. (CoPI), Chen, M. C. (CoPI) & Lee, W. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cardiomyopathy 100%

• Symmetry-Based Deep Learning Applying on Correlation between Nasal Structure and Complaints of Empty Nose Syndrome Patients

  Wan, S.-Y. (PI), Fu, C. H. (CoPI) & Lee, T.-J. (CoPI)

  01/08/22 → 31/07/23

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Syndrome 100%

• Insight into the Replication of Rna Viruses by Spatiotemporal Analyses of Virus-Host Interaction

  Lee, K.-M. (PI) & Huang, Y.-C. (CoPI)

  01/11/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • RNA Virus 100%
  • Virus Cell Interaction 100%

• Merging Nhird and Basic Study to Create the Novel Screening Platform of Anti-Prostate Cancer Herbs-The Role and Mechanism of Astragalus Polysaccharides on Pd-1/Pd-L1 Immunotherapy and Ferroptosis of Prostate Cancer

  Wu, C.-Y. (PI), Kang, H.-Y. (CoPI) & Yang, Y.-H. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Ferroptosis 100%
  • Astragalus 100%
  • Prostate Cancer 100%
  • Immunotherapy 100%
  • Polysaccharide 100%

• Genetic Biomarkers of Child Language Disorder in Taiwan

  Chen, C.-L. (PI), Chang, C. J. (CoPI), Chung, W.-H. (CoPI), Lee, Y.-S. (CoPI), Lin, K. L. (CoPI), Lin, J. L. (CoPI) & Lu, J. J. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Genetics 100%
  • Language Development 100%
  • Language Disability 100%
  • Biological Marker 100%

• Differentially methylated regions (DMRs) regulates GLP-1 analogue in glucose control and clinical response

  Lin, C.-H. (PI), Huang, Y. Y. (CoPI), Lee, Y.-S. (CoPI) & Tsai, C.-N. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Differentially Methylated Regions 100%
  • Glucagon-Like Peptide-1 100%

• Dysregulation of Dna Damage Response by Ubiquitinated Androgen Receptor Aggregates: Mechanisms and Therapeutic Applications of Kennedy’S Disease

  Kang, H.-Y. (PI), Chang, K.-H. (CoPI), Chuang, S. H. (CoPI) & Yang, J. L. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Disease 100%
  • Androgen Receptor 100%

• To Study Sox4 Mediated Cellular Metabolism in Cell Stemness, Invasion, and Drug Sensitivity in Hepatocellular Carcinoma

  Tsai, C.-N. (PI) & Yu, M. C. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cell Metabolism 100%
  • Drug Sensitivity 100%

• Nano/Microparticle Loaded with Human Pluripotent Stem Cell-Derived Exosomes from Selective Tuning of Elastin-Like Polypeptides Coated Plate for Accelerating Wound Care in Diabetes

  Lee, C.-H. (PI), Hsieh, M. J. (CoPI) & Pang, J.-H. S. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Microparticle 100%
  • Elastin 100%
  • Polypeptide 100%
  • Wound 100%

• Efficacy of Low-Energy Extracorporeal Shock Wave in the Treatment of Adenine-Induced Chronic Kidney Disease in Rats

  Hsiao, C.-C. (PI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Chronic Kidney Disease 100%
  • Extracorporeal 100%
  • Adenine 50%
  • Shock (Circulatory) 50%
  • Shock Wave 50%

• Study of the Coordinated Assembly of Kshv Lytic Dna Replication Proteins

  Chang, P.-J. (PI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Replication Protein 100%

• Evaluation of Fgf19 Role in Cholangiocarcinoma and Application the Newest Vitamin D Analog, Mart-11, to Treat Cholangiocarcinoma

  Pang, J.-H. S. (PI) & Juang, H.-H. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Bile Duct Carcinoma 100%
  • Vitamin D Analogue 100%

• Clinical and Inflammatory Features of Patients with Recurrent Chronic Rhinosinusitis and Nasal Polyp

  Huang, C.-C. (PI), Chang, P. H. (CoPI), Huang, C. C. (CoPI), Lee, T.-J. (CoPI) & Wu, P.-W. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Nasal Polyp 100%
  • Chronic Rhinosinusitis 100%
  • Nose Polyp 100%

• The Use of Chinese Herbal Medicine for Diabetic Nephropathy through Cell Cycle Modulation: Big Data Analysis and Experiment Validation

  Chen, H.-Y. (PI), Chen, Y. C. (CoPI), Lin, Y. H. (CoPI), Pang, J.-H. S. (CoPI), Wu, Y.-H. (CoPI) & 高銓澤 (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Diabetic Nephropathy 100%
  • Chinese Herbal Medicine 100%
  • Cell Cycle 100%

• Genomic Alterations in Young Aged Head and Neck Cancer: from Phenotypic Variability to Genetic Susceptibility

  Huang, S.-F. (PI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Genetic Susceptibility 100%
  • Genomics 50%

• Exploring the Recovery Trajectory and Relationships of the Postoperative Pain, Rest/ Mobilization, Food Intake, and Health Outcome after Surgery among Living Liver Donors

  Weng, L.-C. (PI), Chen, K.-H. (CoPI), Huang, H.-L. (CoPI), Lee, W.-C. (CoPI), Tsai, Y.-H. (CoPI), Tsai, P. C. (CoPI) & Yang, T.-Y. (CoPI)

  01/08/21 → 31/07/22

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Health Outcomes 100%
  • Food Intake 100%
  • Postoperative Pain 100%