Projects per year
Personal profile
Education
Courses
New Frontier of Immunology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Human genetic infectious disease
- Human innate immunity
- Infectous diseases
- Primary immunodeficiency
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Collaborations and top research areas from the last five years
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Autoantibodies against Interferons Underlying Infectious Diseases
Ku, C.-L. (PI), Lei, W. T. (CoPI) & Tu, K. H. (CoPI)
01/01/24 → 31/12/24
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Epitopes of Anti-Gm-Csf Autoantibody and Their Corresponding Downstream Signal Regulation
Wang, S.-Y. (PI) & Ku, C.-L. (CoPI)
01/08/23 → 31/07/24
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Limination of the Anticytokine Autoantibody Productizing B Cells by Reengineering Chimeric Autoantibody Receptor T Cells
Ku, C.-L. (PI) & Tu, K. H. (CoPI)
01/08/23 → 31/07/24
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Autoantibodies against Interferons Underlying Infectious Diseases
Ku, C.-L. (PI), Lei, W. T. (CoPI) & Tu, K. H. (CoPI)
01/01/23 → 31/12/23
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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The Anti-Type I Interferon Autoantibodies in Humans Predispose to Infectious Diseases
Ku, C.-L. (PI), Kuo, C.-Y. (CoPI) & Tu, K. H. (CoPI)
01/08/22 → 31/07/23
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
Research output
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Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, COVID Human Genetic Effort, COVID Human Genetic Effort & COVIDeF Study Group, 06 01 2024, In: Genome Medicine. 16, 1, p. 6 6.Research output: Contribution to journal › Comment/debate
Open Access -
Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children
COVID Clinicians, GEN-COVID Study Group & COVID Human Genetic Effort, 05 02 2024, In: Journal of Experimental Medicine. 221, 2, e20231353.Research output: Contribution to journal › Journal Article › peer-review
Open Access8 Scopus citations -
Immunophenotyping and Therapeutic Insights from Chronic Mucocutaneous Candidiasis Cases with STAT1 Gain-of-Function Mutations
Lei, W.-T., Lo, Y.-F., Tsumura, M., Ding, J.-Y., Lo, C.-C., Lin, Y.-N., Wang, C.-W., Liu, L.-H., Shih, H.-P., Peng, J.-J., Wu, T.-Y., Chan, Y.-P., Kang, C.-X., Wang, S.-Y., Kuo, C.-Y., Tu, K.-H., Yeh, C.-F., Hsieh, Y.-J., Asano, T. & Chung, W.-H. & 2 others, , 23 08 2024, In: Journal of Clinical Immunology. 44, 8, p. 184Research output: Contribution to journal › Journal Article › peer-review
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Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals
CONSTANCES cohort, 15 04 2024, In: Journal of Clinical Investigation. 134, 8, e178263.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
The Pathogenic Role of Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Nocardiosis with the Central Nervous System Involvement
Lo, Y.-F., Wang, S.-Y., Wu, Y.-H., Ho, M.-W., Yeh, C.-F., Wu, T.-Y., Peng, J.-J., Lin, Y.-N., Ding, J.-Y., Shih, H.-P., Lo, C.-C., Chan, Y.-P., Rau, C.-S., Kuo, C.-Y., Tu, K.-H., Lei, W.-T., Chen, Y.-C. & Ku, C.-L., 12 08 2024, In: Journal of Clinical Immunology. 44, 8, p. 176Research output: Contribution to journal › Journal Article › peer-review
Prizes
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2016 Outstanding Immunology Scholar Award
Ku, C.-L. (Recipient), 2016
Prize: Outstanding Immunology Scholar Award
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2017Academia Sinica Early-Career Investigator Research Achievement Award
Ku, C.-L. (Recipient), 2017
Prize: Academia Sinica Early-Career Investigator Research Achievement Award
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2018 Outstanding Technology Transfer Contribution Award
Wu, M.-H. (Recipient) & Ku, C.-L. (Recipient), 2018
Prize: Outstanding Technology Transfer Contribution Award
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2020 Outstanding Research Award
Lai, J.-Y. (Recipient), Hsieh, S.-Y. (Recipient) & Ku, C.-L. (Recipient), 2020
Prize: Outstanding Research Award