Jan-Kan Chen

Projects

Projects per year 1984 1993 2005 2006 2007 2015

• 41 Finished

Projects per year

Search results

• Finished

  Study of the Mechanism Underlying the Regulation of the Alternative Splicing of YAP1 pre-mRNA in Human Cancer Cell Lines

  Chen, J.-K. (PI)

  01/08/14 → 31/07/15

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • YAP1 100%
  • Cancer Cell 100%
  • Precursor mRNA 100%
  • Alternative Splicing 100%
  • Cancer Cell Line 100%

• The Use of Metabonomic Approach to Understand the Metabolic Disorders in Diabetic Rats and the Therapeutic Benefits of Resveratrol in Rats

  Chen, J.-K. (PI)

  01/08/13 → 31/07/14

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Metabolic Disorder 100%
  • Resveratrol 100%
  • Diabetes Mellitus 100%
  • Rat 100%
  • Inflammation 27%

• Compensatory Roles of Tap63 in P53-Deficent Cancer Cells

  Chen, J.-K. (PI)

  01/08/12 → 31/07/13

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • P53 100%
  • Promoter Region 33%
  • Cell Line 22%
  • Doxorubicin 16%

• The Roles of Tap63 in P53-Expressing and P53-Deficient Cancer Cells under Genotoxic Stress.

  Chen, J.-K. (PI)

  01/08/11 → 31/07/12

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • P53 100%
  • Cell Cycle Regulation 16%
  • Promoter Region 16%
  • Cell Line 16%

• Regulation of Nanog Expression by Protein Kinase Cs in Human Embryonal Carcinoma Cell (II)

  Chen, J.-K. (PI)

  01/08/10 → 31/07/11

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Nanog 100%
  • Protein Kinases 100%
  • Embryonic Stem Cell 85%
  • Cellular Differentiation 28%
  • Embryogenesis 14%

• Regulation of Nanog Expression by Protein Kinase Cs in Human Embryonal Carcinoma Cell

  Chen, J.-K. (PI)

  01/08/09 → 31/07/10

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Nanog 100%
  • Protein Kinases 100%
  • Embryonic Stem Cell 60%
  • Cellular Differentiation 20%
  • Isoform 10%

• A Study of the Mechanism Underlying the Regulation of TAp63 and Delta Np63 Expressions

  Chen, J.-K. (PI)

  01/08/08 → 31/07/09

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • P53 100%
  • Keratinocyte 100%
  • Protein P53 100%
  • Isoform 66%
  • Promoter Region 33%

• Effects of Exercise on Apoptosis, Metastasis, and Thrombosis of Nasopharyngeal Carcinoma Cell Mediated by Platelet and Natural Killer Cell

  Wang, J.-S. (PI), Chen, J.-K. (CoPI), Chow, S.-E. (CoPI) & Wong, A.M.-K. (CoPI)

  01/08/08 → 31/07/09

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombosis 100%
  • Platelet 100%
  • Programmed Cell Death 100%
  • Nasopharynx Carcinoma 100%
  • Carcinoma Cell 100%

• The Role of Lumican in Cardiovascular System

  Chu, P.-H. (PI) & Chen, J.-K. (CoPI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Lumican 100%

• Overexpression of Stomatin-Like Protein 2 in Human Lung Cancer Cells---Mechanism of Proliferation Regulation and Clinical Significance

  Yang, C.-T. (PI) & Chen, J.-K. (CoPI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cancer Cell 100%
  • Stomatin 100%
  • Lung Cancer 100%

• A Study of the Mechanism Underlying the Regulation of TAp63 and Delta Np63 Expressions

  Chen, J.-K. (PI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • P53 100%
  • Keratinocyte 100%
  • Protein P53 100%
  • Isoform 66%
  • Promoter Region 33%

• Effects of Exercise on Apoptosis, Metastasis, and Thrombosis of Nasopharyngeal Carcinoma Cell Mediated by Platelet and Natural Killer Cell

  Wang, J.-S. (PI), Chen, J.-K. (CoPI), Chow, S.-E. (CoPI) & Wong, A.M.-K. (CoPI)

  01/08/07 → 31/07/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombosis 100%
  • Platelet 100%
  • Programmed Cell Death 100%
  • Carcinoma Cell 100%
  • Metastatic Carcinoma 100%

• Role of EBV in Human Normal Epithelial Cell Differentiation (III)

  Chang, Y.-S. (PI), Chen, J.-K. (CoPI) & Hao, S.-P. (CoPI)

  01/05/07 → 30/04/08

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cellular Differentiation 100%
  • Normal Human 100%

• Promoter Hypermethylation of Wnt Inhibitory Factor-1 in Cells from Lung Cancer-Related Malignant Pleural Effusions---Clinical Significance and Interactions with Epidermal Growth Factor Receptor Mutations

  Yang, C.-T. (PI) & Chen, J.-K. (CoPI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Promoter Region 100%
  • Clinical Significance 100%
  • Lung Cancer 100%
  • Malignant Pleural Effusion 100%
  • Epidermal Growth Factor Receptor 100%

• The Interactions between Angiogenesis and Coagulopathy

  Chu, P.-H. (PI) & Chen, J.-K. (CoPI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Blood Clotting Disorder 100%

• A Study of the Mechanism Underlying the Regulation of TAp63 and Delta Np63 Expressions

  Chen, J.-K. (PI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Expression 100%

• Effects of Exercise on Apoptosis, Metastasis, and Thrombosis of Nasopharyngeal Carcinoma Cell Mediated by Platelet and Natural Killer Cell

  Wang, J.-S. (PI), Chen, J.-K. (CoPI), Chow, S.-E. (CoPI) & Wong, A.M.-K. (CoPI)

  01/08/06 → 31/07/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Thrombosis 100%
  • Nasopharynx Carcinoma 100%

• Role of EBV in Human Normal Epithelial Cell Differentiation (II)

  Chang, Y.-S. (PI), Chen, J.-K. (CoPI) & Hao, S.-P. (CoPI)

  01/05/06 → 30/04/07

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cellular Differentiation 100%
  • Normal Human 100%

• Roles of p63 in the Regulation of Limbal Epithelial Stem Cell Differentiation and Proliferation

  Chen, J.-K. (PI)

  01/08/05 → 31/07/06

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Cell Proliferation 100%
  • Cell Differentiation 100%
  • Stem Cell 100%

• Molecular Mechanisms of Interactions among Gefitinib, Paclitaxel and Stat-3 Blocker Against Human Lung Cancer Cells with or without Mutations in Epidermal Growth Factor Receptor

  Yang, C.-T. (PI), Chen, J.-K. (CoPI), Hung, M.-S. (CoPI), Lee, K.-D. (CoPI) & Lin, Y. C. (CoPI)

  01/08/05 → 31/07/06

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Gefitinib 100%
  • Paclitaxel 100%
  • Lung Cancer 100%
  • Epidermal Growth Factor Receptor 100%

• Role of EBV in Human Normal Epithelial Cell Differentiation (I)

  Chang, Y.-S. (PI), Chen, J.-K. (CoPI) & Hao, S.-P. (CoPI)

  01/05/05 → 30/04/06

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Epithelial Cell 100%
  • Cell Differentiation 100%
  • Epstein Barr Virus 100%
  • Normal Human 100%
  • Cellular Differentiation 100%

• Silencing of Survivin Gene by Adenovirus-Delivered Interfering RNA for Lung Cancer Treatment

  Yang, C.-T. (PI) & Chen, J.-K. (CoPI)

  01/08/04 → 31/07/05

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Adenoviridae 100%
  • Survivin 100%
  • Lung Cancer 100%

• Expression Status of p63 Isoforms in Lung Cancer and Its Effect on p53 Function (III)

  Chen, J.-K. (PI)

  01/08/04 → 31/07/05

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Protein P53 100%
  • Lung Cancer 100%

• Expression Status of p63 Isoforms in Lung Cancer and Its Effect on p53 Function (II)

  Chen, J.-K. (PI)

  01/08/03 → 31/07/04

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Protein P53 100%
  • Lung Cancer 100%

• Expression Status of p63 Isoforms in Lung Cancer and Its Effect on p53 Function (I)

  Chen, J.-K. (PI)

  01/08/02 → 31/07/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Isoform 100%
  • P53 100%
  • Protein P53 100%
  • Lung Cancer 100%

• Development of the Tissue Engineered Cornea (I)

  Tsai, R.J.-F. (PI), Chen, J.-K. (CoPI), Lee, H. (CoPI), Lin, K.-H. (CoPI), Tsao, Y.-P. (CoPI) & Yang, C.-M. (CoPI)

  01/08/02 → 31/12/03

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Engineered Tissue 100%

• Plasma Antioxidant Levels and Atherosclerosis (II)

  Chen, J.-K. (PI)

  01/08/01 → 31/07/02

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Blood Plasma 100%
  • Atherosclerosis 100%
  • Antioxidant 100%
  • Antioxidant Agent 100%

• Plasma Antioxidant Levels and Atherosclerosis (I)

  Chen, J.-K. (PI)

  01/08/00 → 31/07/01

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Atherosclerosis 100%
  • Antioxidant 100%

• Resistance of Human Nasopharyngeal Carcinoma Cells to the Antiproliferative Effect of TGF-Beta---A Mechanistic Inquiry (III)

  Chen, J.-K. (PI)

  01/08/99 → 31/07/00

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Nasopharynx Carcinoma 100%
  • Transforming Growth Factor Beta 100%

• Resistance of Human Nasopharyngeal Carcinoma Cells to the Antiproliferative Effect of TGF-Beta---A Mechanistic Inquiry (I)

  Chen, J.-K. (PI)

  01/08/97 → 31/07/98

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Transforming Growth Factor Beta 100%
  • Nasopharynx Carcinoma 100%

• 人類腦癌細胞裏一個被PDGF受體徵召及磷酸化的40KDA蛋白分子的特性研究

  Chen, J.-K. (PI)

  01/08/96 → 31/07/97

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Pitch (Inclination) 100%
  • Convection 100%
  • Investigation 100%
  • Region 100%
  • Taiwan 100%

• A Mechanistic Study on the Inhibition of the Growth of a Human Nasophoryngeal Carcinoma Cell Line by bFGF

  Chen, J.-K. (PI)

  01/08/95 → 31/07/96

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Carcinoma 100%

• A Mechanistic Study on the Inhibition of Human Nasopharyngeal Carcinoma Cell Growth by bFGF

  Chen, J.-K. (PI)

  01/08/94 → 31/07/95

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Nasopharynx Carcinoma 100%

• Basic and Clinical Collaborating Research Center for Coronary and Hypertensive Cardiovascular Disease

  Chen, J.-K. (PI), Lau, Y.-T. (CoPI), Wu, D.-L. L. (CoPI), Wu, J. H. (CoPI) & Yang, C.-M. (CoPI)

  01/07/94 → 30/06/95

  Project: Ministry of Health and Welfare › Ministry of Health and Welfare Commission Research

  • Cardiovascular Disease 100%

• Effect of Stroma on the Growth and Differentiation of Epithelial Cells in a Living Conjunctival Equivalent

  Chen, J.-K. (PI)

  01/07/93 → 30/06/96

  Project: Ministry of Health and Welfare › Ministry of Health and Welfare Commission Research

  • Stroma 100%
  • Epithelial Cell 100%

• Effect of Stroma on the Growth and Differentiation of Epithelial Cells in a Living Conjunctival Equivalent

  Chen, J.-K. (PI)

  01/07/93 → 30/06/96

  Project: Ministry of Health and Welfare › Ministry of Health and Welfare Commission Research

  • Stroma 100%
  • Epithelial Cell 100%

• Autocrine Property of a Hunan Nasopharyngel Carinoma Cell

  Chen, J.-K. (PI)

  01/02/93 → 31/01/94

  Project: National Science and Technology Council › National Science and Technology Council Academic Grants

  • Project 100%
  • Cells 100%

• Basic and Clinical Collaborating Research Center for Corona for Coronary and Hypertensive Cardiovascular Diseaser in Chang-Gung Medical College

  Chen, J.-K. (PI), Lau, Y.-T. (CoPI), Wu, D.-L. L. (CoPI), Wu, J. H. (CoPI) & Yang, C.-M. (CoPI)

  01/07/92 → 30/06/93

  Project: Ministry of Health and Welfare › Ministry of Health and Welfare Self Research

  • Cardiovascular System 100%

• GROWTH AND PROTEOGLYCAN METABOLISM OF HUMAN VASCULAR CELLS

  Chen, J.-K. (PI)

  01/01/92 → 31/12/92

  Project: National Institute of Health (NIH) › National Institute of Health (NIH) Research Project

  • Metabolic Pathway 100%
  • Proteoglycan 100%

• TISSUE CULTURE/GROWTH FACTOR STUDY--METABOLIC DISORDERS

  Chen, J.-K. (PI)

  01/03/88 → 29/02/96

  Project: National Institute of Health (NIH) › National Institute of Health (NIH) Research Project

  • Growth Factor 100%
  • Metabolic Disorder 100%
  • Tissue Culture 100%

• ALTERED NUTRITIONAL REQUIREMENTS FOR GROWTH

  Chen, J.-K. (PI)

  15/03/84 → 28/02/86

  Project: National Institute of Health (NIH) › National Institute of Health (NIH) Research Project