Personal profile
Courses
Advanced Biochemistry
Group Discussion for Problem-Based Learning in Basic Medical Education
Education
B.S., Davis,Taiwan
, National Taiwan Normal University,
Keywords
- Molecular Oncology, Cell biology, Epigenetics、Gene Regulation, Cell Metabolism
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Epigenetic Regulation of Neuroendocrine Transdifferentiation via the Ar-Cxxc4-Tet2 Axis
Wang, L.-Y. (PI) & Hsu, H. C. (CoPI)
01/08/25 → 31/07/26
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Exploring the Intermediate State of Therapy-Induced Neuroendocrine Prostate Cancer through Dissecting the Ar Noncanonical Roles
Wang, L.-Y. (PI), Hsu, H. C. (CoPI) & Kung, H. J. (CoPI)
01/08/24 → 31/07/25
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Ar-V7 Associated Histone Modification and Metabolic Alterations in Enzalutamide Resistant Prostate Cancer
Wang, L.-Y. (PI)
01/08/22 → 31/07/23
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Ar-V7 Associated Histone Modification and Metabolic Alterations in Enzalutamide Resistant Prostate Cancer
Wang, L.-Y. (PI)
01/08/21 → 31/07/22
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Ar-V7 Associated Histone Modification and Metabolic Alterations in Enzalutamide Resistant Prostate Cancer
Wang, L.-Y. (PI)
01/08/20 → 31/07/21
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Novel function of GTPBP2 in promoting hepatocellular carcinoma progression through inhibition of BTRC-mediated KRAS degradation
Huang, P. S., Chi, H. C., Lin, Y. H., Huang, W. C., Liao, W. T., Wang, P. Y., Wang, L. Y., Wang, Y. W., Lin, T. K., Liao, C. J., Chang, C. J., Lay, I. S., Yeh, C. T., Wang, L. H. & Lin, K. H., 03 02 2026, In: Cancer Cell International. 26, 1, 115.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Oral bioavailable ITRI-148 degrades androgen receptor variants and overcomes antiandrogen resistance in advanced prostate cancer
Hung, C. L., Hsu, W. N., Wang, T. C., Chen, W. R., Chen, Y. T., Kuo, Z. K., Hu, T. L., Lin, Y. C., Yeh, H. H., Lin, H. C., Yu, C. J., Fu, C. W., Liu, H. H., Hsu, H. C., Lin, P. H., Pang, S. T., Lai, C. H. & Wang, L. Y., 01 2026, In: Neoplasia (United States). 71, p. 101253 101253.Research output: Contribution to journal › Journal Article › peer-review
Open Access1 Scopus citations -
PROTACs as Therapeutic Modalities for Drug Discovery in Castration-Resistant Prostate Cancer
Wang, L. Y., Hung, C. L., Wang, T. C., Hsu, H. C., Kung, H. J. & Lin, K. H., 23 01 2025, In: Annual review of pharmacology and toxicology. 65, 1, p. 375-396 22 p.Research output: Contribution to journal › Review article › peer-review
Open Access21 Scopus citations -
Targeting SARS-CoV-2 RNA-dependent RNA polymerase with the coumarin derivative BPR2-D2: Evidence from cell-based and enzymatic studies
Tang, W. F., Tsai, H. P., Chin, Y. F., Tsai, S. K., Lin, C. C., Ngo, S. T., Liang, P. H., Jheng, J. R., Hsieh, C. F., Lee, J. C., Chang, Y. H., Chang, T. Y., Lin, C. Y., Lin, G. H., Cai, J. Y., Chen, Y. L., Chen, Y. S., Liu, P. C., Yang, C. M. & Shadbahr, T. & 9 others, , 08 2025, In: Biomedicine and Pharmacotherapy. 189, 118252.Research output: Contribution to journal › Journal Article › peer-review
Open Access2 Scopus citations -
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir
Tang, W. F., Chang, Y. H., Lin, C. C., Jheng, J. R., Hsieh, C. F., Chin, Y. F., Chang, T. Y., Lee, J. C., Liang, P. H., Lin, C. Y., Lin, G. H., Cai, J. Y., Chen, Y. L., Chen, Y. S., Tsai, S. K., Liu, P. C., Yang, C. M., Shadbahr, T., Tang, J. & Hsu, Y. L. & 9 others, , 03 04 2024, In: Antimicrobial Agents and Chemotherapy. 68, 4, p. e0095623Research output: Contribution to journal › Journal Article › peer-review
Open Access8 Scopus citations