Projects per year
Personal profile
Courses
Introduction to Biotechnology Industry
Molecular Cloning
Education
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Cancer Research
- Heart Physiology
- Molecular Virology
- Nucleic Acid Metabolism
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Collaborations and top research areas from the last five years
Projects
- 6 Finished
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Using Conditional Gene Knockout Mice to Study the Importance of Ddx3x in Oogenesis
Lai, M.-C. (PI), Huang, G.-J. (CoPI) & Pi, H.-W. (CoPI)
01/08/23 → 31/07/24
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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To Improve Recombinant Protein Productivity in Chinese Hamster Ovary Cells by Remodeling Mtor Signaling Pathway
Lai, M.-C. (PI)
01/11/21 → 31/10/22
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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Ddx3 Functions in Neural Development through Translational Control
Lai, M.-C. (PI), Huang, G.-J. (CoPI) & Tarn, W. Y. (CoPI)
01/08/21 → 31/07/22
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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The Regulation of Ddx3-Mediated Translation by Phosphorylation during the Cell Cycle
Lai, M.-C. (PI), Tarn, W. Y. (CoPI) & Yu, J.-S. (CoPI)
01/08/19 → 31/07/20
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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To Study the Multiple Roles of Ddx3 in Viral/Bacterial Infections and Inflammation
Lai, M.-C. (PI), Qiu, J.-T. T. (CoPI) & Tarn, W. Y. (CoPI)
01/08/18 → 31/07/19
Project: National Science and Technology Council › National Science and Technology Council Academic Grants
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DDX3 participates in miRNA biogenesis and RNA interference through translational control of PACT and interaction with AGO2
Lai, M. C., Yu, Y. L., Chen, C. N., Yu, J. S., Hung, H. Y. & Chan, S. P., 01 2025, In: FEBS Open Bio. 15, 1, p. 180-195 16 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Hypoxia-induced translation of collagen-modifying enzymes PLOD2 and P4HA1 is dependent on RBM4 and eIF4E2 in human colon cancer HCT116 cells
Li, H. H., Hung, H. Y., Yu, J. S., Liao, Y. C. & Lai, M. C., 02 2025, In: FEBS Journal. 292, 4, p. 881-898 18 p.Research output: Contribution to journal › Journal Article › peer-review
1 Scopus citations -
DDX3 is critical for female fertility via translational control in oogenesis
Tsai, S. Y., Lin, C. H., Jiang, Y. T., Huang, G. J., Pi, H., Hung, H. Y., Tarn, W. Y. & Lai, M. C., 17 11 2024, In: Cell Death Discovery. 10, 1, p. 472 472.Research output: Contribution to journal › Journal Article › peer-review
Open Access1 Scopus citations -
DDX3 interacts with USP9X and participates in deubiquitination of the anti-apoptotic protein MCL1
Lai, M. C., Chen, Y. P., Li, D. A., Yu, J. S., Hung, H. Y. & Tarn, W. Y., 02 2022, In: FEBS Journal. 289, 4, p. 1043-1061 19 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access8 Scopus citations -
Translation control of Enterovirus A71 gene expression
Lai, M. C., Chen, H. H., Xu, P. & Wang, R. Y. L., 08 01 2020, In: Journal of Biomedical Science. 27, 1, 22.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations