A Mechanistic Investigation on a Putative Immune Checkpoint Ppil-5 for Moderation of Inflammation in Severe Influenza

Avijit, Dutta (PI)
Huang, Ching Tai (CoPI)
Hung, Chen Yiu (CoPI)

Research Center for Emerging Viral Infections

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

新興呼吸道傳染病例如COVID-19是一個重要的醫療問題，免疫失調是這些疾病重症的重要機轉。需要深入研究尋找新的治療方式來改善治療效果。我們期望透過研究PPIL-5 在 CD4+ T 細胞的角色，了解 PPIL-5 對流感感染肺臟發炎之調控效果，以及它治療疾病的可能性。

Project IDs

Project ID:PC11107-5711
External Project ID:MOST111-2314-B182-029

Status	Finished
Effective start/end date	01/08/22 → 31/07/23

Keywords

PPIL-5
immune checkpoint
lung inflammation
Severe influenza
HA-specific T cells.

Access Project

https://www.grb.gov.tw/search/planDetail?id=14513993