Ar-V7 Associated Histone Modification and Metabolic Alterations in Enzalutamide Resistant Prostate Cancer

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本計畫旨在探討雄激素受體剪接變異體在抗性攝護腺癌中如何被調控而導致高度表現。而其高度表現如何在腫瘤細胞中影響細胞代謝活動,進而促進抗藥性的發生。此研究結果在癌症生物學上,將對雄激素受體的剪接作用及其背後表觀遺傳學的作用機制提供新的證據。同時,將為未來針對抗藥性攝護腺癌的臨床治療及藥物發展提供新的策略。

Project IDs

Project ID:PC11008-0227
External Project ID:MOST109-2320-B182-015-MY3
StatusFinished
Effective start/end date01/08/2131/07/22

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