Cadmium-Free Quantum Dot Syntheses by Microfluidic Reaction and Their Applications in Bioimaging and Biosensing

The goal of this research project is to synthesize cadmium-free core/shell quantum dot (CFC/S QD) materials that can emit photoluminescence in near infrared region and can be used in bioimaging and biosensing, to develop related microfluidic synthesis technologies, to functionalize these CFC/S QDs through ligand modification and bio-conjugation, and to finally apply these bioconjugated CFC/S QDs in in vitro bioimaging and biosensing of Staphylococcus aureus. In addition, the effects of composition, size, structure of quantum dots as well as process conditions of microfluidic reaction, surface ligand modification, and bioconjugation on the characteristics of CFC/S QDs and the performance of bioconjugated CFC/S QDs in in vitro bioimaging and biosensing will also be investigated in order to improve the characteristics and performance of these bioconjugated CFC/S QDs. It is hope that these efforts can lead to eventual applications of these bioconjugated CFC/S QDs in biological research area including biophotonics and nanomedicine.

Project ID:PB10708-1784
External Project ID:MOST107-2221-E182-079