Combining Suture-Reinforced High Resilent Aligned Nanofibrous Yarn/Membrane and Their Hierarchically Assembled Fascicle Mimicking Scaffolds with Biochemical and Physical Cues for Tendon Tissue Engineering

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本研究將發展新的臨床治療方式,開發新型態適合肌腱組織再生的組織工程支架,為肌腱修復的相關治療方式,提供更具潛力的做法。並且以生化訊息因子結合物理訊息因子,以加速植入於支架中肌腱細胞快速生成正常肌腱組織。最後以兔子肌腱缺損修復,實際模擬臨床上肌腱修復手術進行方式,以利於臨床的應用,改善目前臨床所遭遇到的問題。

Project IDs

Project ID:PC11008-0503
External Project ID:MOST109-2314-B182-013-MY3
StatusFinished
Effective start/end date01/08/2131/07/22

Keywords

  • Tendon
  • tissue engineering
  • scaffold
  • electrospinning
  • yarn
  • fibroblast growth factor
  • tenocyte
  • fascicle
  • dynamic cell culture

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