Cost-Effectiveness of Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer Patients with Different Pathological Stages

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details


Background: The incidence of esophageal cancer has continuously increased and overall survival has been poor. Esophagectomy is the one of main treatment for patients with esophageal cancer. Open esophagectomy (OE) has not only has a higher morbidity and mortality, but also has a higher rate of complications. Minimally invasive esophagectomy (MIE) can provide similar effects to patients treated with open esophagectomy and can have a lower incidence of complications. Objective: This study aims to evaluate the cost-effectiveness between OE and MIE for esophageal cancer patients with different pathological stages. Method: This study links National Health Insurance database, cancer registry and cause of death to perform MIE and OE for the cost-effectiveness of treating patients with different pathological stages of esophageal cancer. The results of the cost-effectiveness analysis will be presented as an incremental cost-effectiveness ratio and a cost-effectiveness acceptability curve. The bootstrap method is used to assess variations of incremental cost-effectiveness ratio. Expected Results: The results of cost-effectiveness analysis of MIE and OE should be published in international journals and provided to government medical related departments for reference in policy formulation and planning.

Project IDs

Project ID:PF10907-2354
External Project ID:MOST109-2410-H182-003
Effective start/end date01/08/2031/07/21


  • esophageal cancer
  • open esophagectomy
  • minimally invasive esophagectomy
  • cost-effectiveness analysis


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