Covr/Covs Two-Component Regulatory System and Quorum-Sensing Regulator Rgg on Modulating Extracellular Vesicle Production under Acidic Stress in Group a Streptococcus( III )

Chiang-Ni, Chuan (PI)
Wu, Jiunn Jong (CoPI)

Department of Microbiology and Immunology

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

胞外囊泡已知在細菌生理及致病過程中均扮演重要的角色。A群鏈球菌每年在全球造成超過16萬人死亡，近年並於亞洲及歐洲等地造成猩紅熱疫情。雖然已知A群鏈球菌可釋出胞外囊泡，但胞外囊泡釋出的調控及其在致病過程中的角色均未被釐清。本計劃為A群鏈球菌胞外囊泡整合型計劃子計劃之一，研究成果將提供胞外囊泡的調控機制，以及胞外囊泡在細菌毒力因子的釋出、細胞間訊息傳遞及水平基因轉移之角色等資訊，可增加我們對胞外囊泡影響A群鏈球菌演化及致病能力之了解。

Project IDs

Project ID:PC11208-0055
External Project ID:MOST112-2320-B182-002

Status	Finished
Effective start/end date	01/08/23 → 31/07/24

Keywords

Streptococcus pyogenes
Gram-positive bacterial extracellular vesicle
Bacterial two-component regulatory system
Bacterial quorum-sensing system

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https://www.grb.gov.tw/search/planDetail?id=15567971

Covr/Covs Two-Component Regulatory System and Quorum-Sensing Regulator Rgg on Modulating Extracellular Vesicle Production under Acidic Stress in Group a Streptococcus( III )

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