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Deciphering the Multifaceted Role of Tmem165 in Picornavirus Replication

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

執行本計畫之目的在於深入研究TMEM165在小RNA病毒複製中的角色,特別是其在病毒複製胞器形成、離子平衡調節及自噬生成過程中的影響。通過使用CRISPR-Cas9基因編輯技術,我們旨在揭示TMEM165在病毒感染過程中的具體機制,以期為廣效抗病毒藥物的開發提供新的靶點。

Project IDs

Project ID:PC11311-1886
External Project ID:NSTC113-2320-B182-032
StatusFinished
Effective start/end date01/11/2431/10/25

Keywords

  • Transmembrane protein 165 (TMEM165)
  • picornavirus infection
  • replication organelle
  • ion homeostasis
  • autophagy biogenesis

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