Development of an Integrated, Instrument-Free, User-Friendly, and Low-Cost Paper-Based Point-Of-Care Test Device Capable of Performing Isothermal Nucleic Acid Amplification Test under Resource-Limited Condition- Its Use in Gonorrhea Detection and Antibiotic Resistance Test of the Pathogenic Bacteria

Wu, Min-Hsien (PI)

Department of Biomedical Engineering

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

全球傳染病接續流行，加上多重抗藥性的超級細菌威脅，這無疑地對全球公衛及醫療體系帶來挑戰。為了快速檢測疾病並控制其蔓延，世界衛生組織認為在資源有限的環境，提供快速、易操作、準確與低成本的即時檢測是必要的。以核酸為基礎的病原檢測被認為適合傳染病的管控。然而，傳統的核酸檢測，並不適合實驗室以外的情境。為此，我們提出了一項紙式等溫核酸擴增即時檢測裝置，它將樣品前處理、核酸擴增與即時檢測等操作，整合於一項紙基式微流體裝置上，其目標係實現無設備需求、準確、快速、易操作、且"消費者可負擔"的等溫核酸擴增即時檢測平台。該裝置除了可應用於公衛或醫療領域外，它亦可應用於環保、國防、食安、或其它工業領域。

Project IDs

Project ID:PB11207-4659
External Project ID:NSTC112-2221-E182-039-MY2

Status	Finished
Effective start/end date	01/08/23 → 31/07/24

Keywords

Paper-based microfluidic technology
Paper-based analytical device (PAD)
Isothermal nucleic acid amplification test (iNAAT)
Point-of-care test (POCT)
Sexually transmitted infections (STIs)

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https://www.grb.gov.tw/search/planDetail?id=15459890

Development of an Integrated, Instrument-Free, User-Friendly, and Low-Cost Paper-Based Point-Of-Care Test Device Capable of Performing Isothermal Nucleic Acid Amplification Test under Resource-Limited Condition- Its Use in Gonorrhea Detection and Antibiotic Resistance Test of the Pathogenic Bacteria

Project Details

Abstract

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