Discovering the Glucose/Chrebp/Cxcl12/Cxcr7 Pathways in Human Bladder Cells

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

膀胱纖維化與癌化是國人重大疾病。計畫主要將藉由高糖下對膀胱基質與癌細胞之影響來探討葡萄糖標靶基因SDF1/CXCL12之表現，功能與調控機制於人類膀胱細胞來探索與人類膀胱纖維化與癌化有關之因子。經由此研究所發現之分子機制，期能試圖瞭解膀胱纖維化與癌化之形成，或可提供新的藥物篩檢因子與有關膀胱疾病診斷與治療方向。

Project IDs

Project ID:PC11407-5415
External Project ID:NSTC114-2320-B182-016
StatusActive
Effective start/end date01/08/25 → 31/07/26

Keywords

  • bladder
  • glucose
  • ChREBP
  • CXCL12
  • CXCR7
  • tumorigenesis

Access Project