Discovery and Verification of Exosomal Membrane-Associated Proteins as Novel Plasma Biomarkers for Early Detection and Disease Monitoring of Colorectal Carcinoma

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

大腸直腸癌是威脅國人健康重大疾病之一,現行臨床使用的大腸直腸癌篩檢及術後監控生物標記(如糞便潛血及血液CEA),準確性不佳,亟需研發新穎有效的生物標記以提升大腸直腸癌防治能力。執行本計畫將可深入瞭解大腸直腸癌病患與健康受試者血液中胞外囊泡膜蛋白質分子的變化全貌,據此很有機會開發新穎有效的胞外囊泡膜蛋白生物標記(群),並可進一步與糞便潛血及血液CEA標記結合,輔助醫事人員有效篩檢早期大腸直腸癌或早期偵測癌症復發,達到提升治療效果及降低醫療支出的終極目標。

Project IDs

Project ID:PC11108-0209
External Project ID:MOST109-2320-B182-009-MY3
StatusFinished
Effective start/end date01/08/2231/07/23

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