Project Details
Abstract
頭頸癌是台灣十大癌症之一,而因頭頸癌好發在中年男性,對家庭及社會無形中造成相當大的影響。惡性頭頸癌常因轉移或復發造成不可逆的後果,而細胞之高侵襲性與放射抗性即為此不可逆之主因。本研究中,本計畫擬將探討,ITGA6在檳榔誘發頭頸癌機制中,可能兼具調控細胞侵襲及放射抗性之關鍵分子機制。這些研究成果,可進一步做為日後應用於預測放療效益、預後或分子治療之學理基礎,預期對本土癌症醫學將有學術及社會之貢獻。
Project IDs
Project ID:PC11008-0570
External Project ID:MOST108-2320-B182-029-MY3
External Project ID:MOST108-2320-B182-029-MY3
Status | Finished |
---|---|
Effective start/end date | 01/08/21 → 31/07/22 |
Keywords
- ITGA6
- heqc-neck cancer
- areca nut
- cell invasion
- radioresistance
- molecular mechanism
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