Effects of Cpap Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea: Role of Symptom Subtypes

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

我們的主要方法將應用採用PS設計，以復制隨機觀察到的變量，使選擇偏差(selection bias)最小化，並減少來自非隨機治療組比較的因果推斷(causal interference)。將這種嚴格的方法應用於現實世界數據，使我們能夠解決以前CPAP或牙套治療RCT的兩個主要缺點：1）將嗜睡的OSA患者列入研究，以及2）評估CPAP或牙套治療對患有OSA的患者長期縱向預後的真正益處（相對於非使用者）。了解CPAP或牙套對各種OSA亞型之間24hMBP和心血管生物標誌物的不同作用，是邁向個人化( personalized)OSA治療的重要一步。

Project IDs

Project ID:PC11108-0145
External Project ID:MOST110-2314-B182-059-MY3
StatusFinished
Effective start/end date01/08/22 → 31/07/23

Keywords

  • obstructive sleep apnea syndrome
  • CPAP
  • Outcome. Propensity score (PS) methods

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