Epitopes of Anti-Gm-Csf Autoantibody and Their Corresponding Downstream Signal Regulation

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本計劃目的,是希望可以徹底了解 anti-GM-CSF-Abs 的 epitopes 及對相關下游機轉的影響。除了可以利用本研究預期成果,進一步認識目前anti-GM-CSF-Abs的兩個疾病:C. gattii infection及PAP,在致病機轉上的異同處外,也由於GM-CSF 在人體多種病症的表現及進展都有角色,如果我們可以透底了解其作用,或許我們目前選殖出的這些 human monoclonal anti-Gm-CSF-Ab 就有機會對將來的臨床治療造成影響,尤其是對葯物發展上的頁獻。

Project IDs

Project ID:PC11207-2236
External Project ID:NSTC112-2314-B182-017
StatusFinished
Effective start/end date01/08/2331/07/24

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