Evaluation of Clinical Efficacy and Pharmacological Mechanism of a Mixed Chinese Herbal Formula in Atopic Dermatitis Patients by Integrating Metabolomics and Pharmacokinetic Analysis( II )

Yang, Sien-Hung (PI)
Fu, Shu Ling (CoPI)
Hsu, Peiyu (CoPI)
Kung, Yen Ying (CoPI)
Li, Chia Jung (CoPI)
Lin, Jr-Rung (CoPI)
Lin, Mei Jiun (CoPI)
Lin, Chao Hsiung (CoPI)
Wang, Pin Han (CoPI)
Wang, Ching Chiung (CoPI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

本研究計畫主要在探討中藥治療異位性皮膚炎的療效，藉由整合型團隊合作，我們可以更了解中藥複方對人體內的免疫調節作用(免疫機轉探討)，中藥複方的藥理機轉(藥物動力學探討)，中藥複方對人體代謝的影響以及與療效相關的代謝物群組(代謝體學分析)，以及中藥的免疫調節是否與腸道菌叢的改變有關係(microbiota分析)，這些研究成果再與受試者的中醫證型相比對，有助於了解中醫針對個體化治療(辨證論治)的理論依據，此成果有助於中醫治療異位性皮膚炎時可依個人體質不同而提供精準化臨床治療，也有助於提供該疾病治療的臨床指引。

Project IDs

Project ID:PC11206-0018
External Project ID:MOST112-2327-B182-005

Status	Finished
Effective start/end date	01/06/23 → 31/05/24

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Evaluation of Clinical Efficacy and Pharmacological Mechanism of a Mixed Chinese Herbal Formula in Atopic Dermatitis Patients by Integrating Metabolomics and Pharmacokinetic Analysis( II )

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