Examination of Selected Evs Membrane Proteins as Novel Salivary Biomarkers for Disease Detection/Monitoring and Reveal of Evs-Mediated Mechanisms for Cancer Progression in Oscc

Chu, Lichieh Julie (PI)
Chang, Kai-Ping (CoPI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

高效能的檢測分子搭配簡便的偵測形式始能將腫瘤生物標誌從基礎研究轉譯至臨床應用，因此我們將驗證唾液的胞外體膜蛋白生物標記，並開發相關檢測法，不僅設計前瞻性試驗來驗證分子效能，亦探討其相關之癌化機制。此研究成果有助於監測口腔癌達到預防醫學之目的，亦可有效降低花費於癌症治療的社會與經濟成本。

Project IDs

Project ID:PC11107-4818
External Project ID:MOST111-2320-B182-030

Status	Finished
Effective start/end date	01/08/22 → 31/07/23

Keywords

oral cancer
extracellular vesicles (EVs)
membrane protein
salivary biomarker
disease monitoring
tumor progression mechanism
multiple reaction monitoring mass spectrometry (MRM-MS)
quantitative proteomics.

Access Project

https://www.grb.gov.tw/search/planDetail?id=14504538