Exosome Mediated Mechanism of Glutamine Deprivation in Metabolic Adaptation

Pai, Li-Mei (PI)

Department of Biochemistry

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

探討腫瘤細胞在缺乏谷氨酸的代謝壓力下釋放外泌體來促進CTP合成酶的線性構造以達到代謝平衡的機制，有助了解腫瘤細胞與腫瘤環境的互動，而提供新的癌症治療標的。

Project IDs

Project ID:PA11107-3601
External Project ID:MOST111-2311-B182-001

Status	Finished
Effective start/end date	01/08/22 → 31/07/23

Keywords

Exosome
CTP synthase
YWHAB
cancer metabolism
enzyme compartmentalization

Access Project

https://www.grb.gov.tw/search/planDetail?id=14506974