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Explore the Cellular Mechanism of Glutamate Synaptic Plasticity on the Regulation of Brain and Behavioral Feminizations in the Hypothalamus of Neonatal Rats: Developmental Changes and the Role of Estradiol

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

成功的腦女性化確保雌性動物能表現正常的行為及生殖力,使物種能持續的繁衍,也有助於維持社會性別結構及秩序。這個研究結果,可增進我們對下視丘神經元的突觸運作造成腦女性化細胞機制的瞭解,也可對特定好發於女性疾病的病因(例如精神疾患好發於青春期少女)及對性別傾向的腦發展提出可能的解釋以促進社會大眾對跨性別家人及朋友的認知與接納,增加學校社會的和諧,及提供政府立法及設立性別友善設施的參考。

Project IDs

Project ID:PC11007-2586
External Project ID:MOST110-2320-B182-014
StatusFinished
Effective start/end date01/08/2131/07/22

Keywords

  • Electrophysiological recording
  • feminization
  • sex differentiation
  • synaptic vesicle
  • glutamate synaptic transmission
  • astrocyte
  • glutamine-glutamate cycle
  • gonadotropin-releasing hormone (GnRH) neuron
  • luteinizing hormone (LH) surge
  • lordosis

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