Explore the Efficacy of Jiawei Xiaoyao San in Preventing Hepatoma Progression Caused by Hepatic Fibrosis and Associated Microenvironment Regulation Mechanism

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

肝癌為台灣國病且致死率相當高；肝癌的發展與惡化與肝臟纖維化/硬化導致之微環境改變息息相關。現今治療肝臟纖維化/硬化或肝癌化療藥物效果不佳且造成醫療資源之重大負擔；因此，開發另類或輔助治療藥物對提昇患者生活品質、降低醫療成本至為關鍵。本計畫以系統生物學深入研究加味逍遙散防治肝臟纖維化/硬化進而控制肝癌惡化之功效與其分子機制；突顯中醫藥多標靶與低毒性之特性並為學術研究提供重要基礎；對於診斷治療、新藥開發或產業升級皆有正面助益。

Project IDs

Project ID:PC11007-4247
External Project ID:MOST108-2320-B182-024-MY3
StatusFinished
Effective start/end date01/08/21 → 31/07/22

Keywords

  • Hepatocellular carcinoma (HCC)
  • Liver fibrosis
  • Microenvironment
  • Jia-Wei-Xiao-Yao-San (JWXYS)
  • System biology

Access Project

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
View full fingerprint