Project Details
Abstract
本研究計畫案主旨於“建立羊水幹細胞誘導形成角膜內皮前驅細胞庫"。期以眼角膜內皮前驅細胞(HCEP)細胞庫之建立,達到ONE-CELL-FOR-ALL的目地,解決長久以來全球角膜捐贈不足的問題。本研究計畫首度將羊水幹細胞誘導形成具增生能力的「角膜內皮前驅細胞」,使得細胞庫得以建立,解決先前誘導角膜內皮細胞無法於體外大量增殖的困境。羊水幹細胞為目前可得最年輕的間質幹細胞、具高分化潛力、且不具tumorigenesis等特性,非常適合作為誘導的細胞來源。本計畫可直接鏈結於臨床試驗,進行細胞再生取代性療法。
Project IDs
Project ID:PC11007-1462
External Project ID:MOST110-2314-B182-050
External Project ID:MOST110-2314-B182-050
Status | Finished |
---|---|
Effective start/end date | 01/08/21 → 31/07/22 |
Keywords
- Human Cornea Endothelial Cell (HCEC)
- Human Amniotic Fluid Stem Cell (AFSC)
- neural crest cell (NCC)
- Human Cornea Endothelial Progenitor (HCEP)
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.