Graphene nanoribbon active biotransistor for clinical application

The Flash-ISFET (FISFET) which combine with the trapping centroid, polarization membrane and graphene nanoribbon is used in this project. The goal of this project is to implement the sensing characteristic of clinical bio-samples such as inflamasome, urinary tract infection and E.coli by using the FISFET, and further investigate the bacterial susceptibility test. To ensure the accuracy of the sensing result of those clinical bio-samples, the shortest sensing time could be expected by applying the FISFET in this project. There are three parts in this project Part I: The development of high selectivity active electrolyte insulator semiconductor (EIS) and reference EIS (ReEIS) 1. The research of trapping centroid in the sensing membrane and establishment of theoretical model and developing the materials of sensing membrane. 2. The research of the high selectivity/high polarization in the sensing membrane and establishment of theoretical model. 3. The development of graphene floating flash memory device. Part II: The development of graphene FISFET 1. The research of doping and oxidation method of graphene material. 2. The development of graphene nanoribbon device. 3. The development and characteristic of graphene FISFET. Part III: The application of the clinical biology testing for the grapheme nanoribbon FISFET 1. The development and characteristic of grapheme nanoribbon FISFET. 2. The golden sample establishment for the grapheme nanoribbon FISFET. 3. The application of clinical bio-samples testing in the grapheme nanoribbon FISFET and the bacterial susceptibility test.

Project ID:PB10202-1052
External Project ID:NSC101-2221-E182-034-MY3