Project Details
Abstract
Disease severity and treatment effectiveness of childhood intermittent exotropia were usually
assessed by the objective indicators as angle of deviation, frequency of intermittent exotropia
and the impact on visual function development. However, the impacts on life, mental health
and development of children lack well-defined indicator. Develop and prospectively follow
up the trends of subjective health-related quality of life (HRQoL) on long-term aspects were
benefit to evaluate the effectiveness of treatment and helpful for children and their family to
cope with disease. The aim of this three-year study was to (1) develop Chinese version of
intermittent exotropia quality of life questionnaire (CIXTQoL) using qualitative interview and
cross-cultural instrument translation and validation method (2) prospectively evaluate the
trends of HRQoL, stereoacuity, angle of deviation, best visual acuity and surgery satisfaction
of the intermittent exotropia children. In first year, intermittent exotropia children and their
family’s experience and illness impact were explored in this qualitative study. Sample was
selected with purposive sampling method and a face to face interview was used to collect data.
Thematic analysis was adopted to deal with the script and text. In second year, a
cross-cultural translation and backward translation of Intermittent Exotropia Questionnaire
(IXTQ)(5-7 years children version and parent version) were developed in this quantitative
study. After combining the items developed in firs year study and items of IXTQ, the
psychometric properties of CIXTQoL were vigorously testing. In third year, a prospective
longitudinal study design was applied. Data of HRQoL, stereoacuity, angle of deviation, best
visual acuity and surgery satisfaction of the intermittent exotropia children were collected
with chart review and structured questionnaire interview methods before surgery, and then
again 3 and 6 months after surgery. The differences of HRQoL score between postoperative
and preoperative scores were compared across timing using General Estimating Equation and
analysis of covariance.
Project IDs
Project ID:PC10501-1553
External Project ID:MOST103-2314-B182-007-MY3
External Project ID:MOST103-2314-B182-007-MY3
Status | Finished |
---|---|
Effective start/end date | 01/08/16 → 31/07/17 |
Keywords
- intermittent exotropia
- children
- health-related quality of life
- scale development
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