Highly Accurate Early Diagnosis, Prognosis, and Drug Screening of Parkinson'S Disease by the Development of Zeptomolar-Level Multichannel Spr Biosensor Utilizing Plasmonic Nanostructures and Deep-Red Oleds( I )

Liu, Kou-Chen (PI)
Chen, Chiung Mei (CoPI)
Chiu, Ching-Chi (CoPI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

本計劃預期能研發出能對臨床血清中α-syn進行高靈敏度（LOD＜4.5ag/ml）和高選擇性（AUC~100%）檢測表面電漿共振生物感測器，並能實現快速檢測（＜15分鐘）和高通量的要求。此感測器有望能用作帕金森氏症的早期診斷或預後，並能滿足常規醫療檢測在臨床量表上的要求。此項目若成功，能及時介入及控制帕金森氏症的發展，不僅能改善老年人的生活質量和預期壽命，還能減輕社會的負擔（在台灣平均每年需花費四千八百萬美元用於治療帕金森），實爲利國利民之舉。

Project IDs

Project ID:PB11207-2940
External Project ID:NSTC112-2221-E182-045

Status	Finished
Effective start/end date	01/08/23 → 31/07/24

Keywords

PD
α-syn
AuNPs
SPR
deep-red OLED

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https://www.grb.gov.tw/search/planDetail?id=15463066

Highly Accurate Early Diagnosis, Prognosis, and Drug Screening of Parkinson'S Disease by the Development of Zeptomolar-Level Multichannel Spr Biosensor Utilizing Plasmonic Nanostructures and Deep-Red Oleds( I )

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Abstract

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