Hydrogen Sulfide as a Reprogramming Approach for Chronic Kidney Disease and Hypertension: a Focus on Gut Microbiota-Derived Metabolites

  • Tain, You-Lin (PI)
  • Hsu, Chien Ning (CoPI)

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本計畫將利用動物模型與慢性腎臟病童的世代研究,在懷孕時產生慢性腎臟病誘發後代長大時出現高血壓與腎臟病,來研究程序化過程中硫化氫路徑、腸道菌叢產生的尿毒素與代謝產物、與腎臟程序化交互作用產生的機轉,我們的結果將針對硫化氫路徑開發新的反轉程序化治療策略,以促進婦幼健康進而減輕日後台灣沉重的健康照護負擔。

Project IDs

Project ID:PC11007-1854
External Project ID:MOST110-2314-B182-020-MY3
StatusFinished
Effective start/end date01/08/2131/07/22

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