Identification and Characterization of Factors Required for Streptococcus Sanguinis and Streptococcus Salivarius to Transform from Symbionts to Pathobionts

Chen, Yi-Ywan Margaret (PI)

Department of Microbiology and Immunology

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

本計畫屬基礎微生物學研究，對社會及經濟無直接影響。但計畫所得將讓我們對共生菌如何轉變為病原菌的基本機制有全面的了解，對如何早期在高危人群中發現潛在共生病原菌，降低醫療成本等有所貢獻。在學術上，計畫所得將加強我們對口腔鏈球菌種的基因組、轉錄組及生理活性的知識，有助於發展診斷標記及治療策略。

Project IDs

Project ID:PC11107-5581
External Project ID:MOST111-2320-B182-027

Status	Finished
Effective start/end date	01/08/22 → 31/07/23

Keywords

oral streptococci
Streptococcus sanguinis
Streptococcus salivarius
transcriptomes
genomes
symbiont-pathobiont transition
biofilm
antiphagocytic activity
stress responses

Access Project

https://www.grb.gov.tw/search/planDetail?id=14512808