Investigate the Potential of Utilizing Bioadhesive Nanoparticle Nasal Spray to Protect and Expedite the Tissue Repair of Nasal Epithelium

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

患有慢性鼻竇炎的患者通常伴隨鼻腔內膜上皮層受損,進而演變成難纏的慢性發炎疾病,導致鼻塞、流膿性鼻涕或嗅覺障礙。手術雖能夠立即緩解症狀,但仍需要靠沖洗鼻腔合併鼻用類固醇來減少復發機會。但類固醇長時間使用也通常伴隨嚴重的副作用。為此本研究的目的在於評估我們新開發的奈米生物膠藥物載體噴劑(NANO-ADC)是否能夠阻絕發炎的產生並促進鼻腔上皮細胞修復,避免後續慢性且難纏的鼻竇炎發生,提供長期受慢性鼻竇炎困擾的患者提供全面且有效的治療選擇。

Project IDs

Project ID:PC11307-1699
External Project ID:NSTC113-2314-B182-017
StatusFinished
Effective start/end date01/08/2431/07/25

Keywords

  • Chronic Sinusitis
  • 3D Cell Culture
  • Nanoparticle drug carrier
  • bioadhesive
  • Re-Epithelization
  • Wound Healing

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