Investigating Cellular Processes and Molecular Regulation Governed by Akt-Related Chemicals to Promote Spinal Cord Recovery after Injury

Cheng, Yi-Chuan (PI)
Chen, Yi Chieh (CoPI)
Huang, Yin Cheng (CoPI)

Graduate Institute of Biomedical Sciences

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

我們發現一種化學物質的組合可在受脊髓損傷的斑馬魚和小鼠中顯著恢復其運動功能。我們的研究將詳細分析該化學組合於AKT訊息傳遞路徑及其下游分子的調控功能，以及該調控如何影響細胞改變以促使脊髓再生，此研究成果將有助於開發治療人類脊髓損傷的新方向。

Project IDs

Project ID:PC11307-2228
External Project ID:NSTC113-2320-B182-029-MY3

Status	Active
Effective start/end date	01/08/24 → 31/07/25

Keywords

Zebrafish
spinal cord injury
spinal cord regeneration
AKT signaling

Access Project

https://www.grb.gov.tw/search/planDetail?id=16585911