Investigating the Drug-Nutrient Interaction of Bioactive Compounds in Dietary Supplements Mediated by the Atp-Binding Cassette Transporters

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

醫療專業人員廣泛認識到,食物與藥物的相互作用可能改變藥物的藥物動力學或藥效學特性,甚至導致不良反應。因此,我們採用系統化分析方法,結合三磷酸腺苷結合盒(ABC)轉運蛋白的結構與特徵,預測其在食物-藥物相互作用中的角色,以深化對這類交互作用的理解。

Project IDs

Project ID:PB11407-13671
External Project ID:NSTC114-2320-B182-005
StatusActive
Effective start/end date01/08/2531/07/26

Keywords

  • Drug-nutrient interaction
  • Dietary supplements
  • ATP-binding cassette transporters
  • P-glycoprotein
  • ABCG2

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