Investigating the Effects and Mechanism of Metformin on Diabetic Bone Pathology

Huang, Kuo-Chin (PI)
Chang, Shun Fu (CoPI)

School of Medicine

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

我們預期降血糖藥物二甲雙胍可以影響腸道微菌叢的多樣性變化，從而調控體內的抗炎機制，改善Th17/Treg細胞的平衡狀態，達成影響糖尿病性骨病的表現與結果。完成本實驗，我們計畫可以進一步釐清出腸道微菌叢中的特定益生菌種，協助改善現行藥物的治療效果；甚者，延伸至骨質疏鬆症的初級預防作業。

Project IDs

Project ID:PC11007-2079
External Project ID:MOST110-2314-B182-006

Status	Finished
Effective start/end date	01/08/21 → 31/07/22

Access Project

https://www.grb.gov.tw/search/planDetail?id=13877967