Limination of the Anticytokine Autoantibody Productizing B Cells by Reengineering Chimeric Autoantibody Receptor T Cells

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

抗丙型干擾素自體抗體疾病好發於台灣地區,且這個疾病與人種特有的 HLA 基因型有關係,此計畫的目標是發展丙型干擾素嵌合自體抗體受體T細胞,藉由抗原特異性的方式,專一的清除病人體內致病性的B細胞,來達到治療感染症的目的。而對於病人的抗丙型干擾素自體反應B細胞的研究也能解析該抗體的組成,了解它們與臨床症狀的相關性,期望可以進一步將研究應用於臨床治療上。

Project IDs

Project ID:PC11207-1336
External Project ID:NSTC112-2320-B182-055-MY3
StatusActive
Effective start/end date01/08/2331/07/24

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.