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Mechanisms Associated with Poor Outcomes of Heart Failure Patients with High Plasma Level of Phenylalanine in Intensive Care Units

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

在心臟加護病房病人的初始研究中發現,苯丙氨酸升高的病人,一年內死亡率升高4倍,但為何增加?如何與死亡相關?原因目前真的不清楚。 本研究欲建立檢測苯丙氨酸的適應症及流程,可進一步對已發現苯丙氨酸升高的病人,有專屬的鑑別原因檢測平台,達到精準醫療的概念。本研究相當符合臨床轉譯性的理念,聚焦於重症病人,在提出一個更精準的風險評估方法後,可以根據分類,找出相對應的病生理學類別,進而發展相對之應介入方法。研究成果希望可改善重症病人的預後,且預期可用在更多不同屬性的重症病人族群或甚至非重症病人族群。

Project IDs

Project ID:PC11107-4535
External Project ID:MOST109-2314-B182-056-MY3
StatusFinished
Effective start/end date01/08/2231/07/23

Keywords

  • phenylalanine
  • heart failure. mortality

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