Microwave-Assisted Synthesis of N-Doped Graphene Nanoribbons for Electrochemical Biosensing Applications

The synthesis and surface functionalization of one-dimensional graphene nanoribbon will be studied for electrochemical biosensor applications. From experimental viewpoint, we plan to use the function called PowerMax in the microwave-assisted synthesis to improve the yield of graphene nanoribbons derived from the unzipping of multi \walled carbon nanotubes. (D. V. Kosynkin et al. Nature 2009, 458, 16.) After we can get large amount of high-quality graphene nanoribbons, we will further fabricated the graphene nanoribbons using single- or double-walled carbon nanoutbes and N-doped graphene nanoribbons. All kinds of graphene nanoribbons will be characterized by different analysis methods so as to be integrated in the electrochemical biosensors. From theoretical viewpoint, we plan to use density functional theory calculation to study the adsorption mechanism and structure between biomolecules on the surface of various graphene nanoribbons. The adsorption mechanism and structure are expected to change and can be manipulated by designed atomistic features on various graphene nanoribbon surfaces. Our research can offer atomistic and molecular theory foundation for future nanodevice and nanosystem applications. Besides our experimental and theoretical experiences in carbon nanotube and graphene in early publications, (Chem. Mater. 2005, 17, 3749. Citation ＞ 100, IF = 6.397, N/M = 5.4%; J. Am. Chem. Soc. 2006, 128, 8368. IF = 9.023, N/M = 5.0%; J. Mater. Chem. 2011, 21, 14622. IF = 5.099, N/M = 16/222 = 7.2%; Biosens. Bioelectron. 2011, 26, 3450. IF = 5.429, N/M = 1/24 = 4.2%) we already have some results which can prove this proposal is doable as well as valuable. (ACS Nano 2011, 5 (10), 7788. IF = 9.855, N/M = 9/222 = 4.1%) It is believed that we must be able to contribute to the development of nanocarbon materials with significant research achievement and publications.

Project ID:PB10108-2817
External Project ID:NSC101-2221-E182-062