Modulating the Functions of Ns2 of Influenza a Virus by Deubiquitinase Otub1

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

本研究透過探討宿主蛋白質去泛素酶OTUB1如何調控A型流感病毒NS2蛋白質的後轉譯修飾，而增進病毒基因體複製，病毒基因體運送出細胞核組裝，以及影響免疫反應的機制。了解此調控機制，將能進一步發展抑制病毒生成的策略，減低A型流感病毒流行性傳播與感染。

Project IDs

Project ID:PC11207-1382
External Project ID:NSTC112-2320-B182-033
StatusFinished
Effective start/end date01/08/23 → 31/07/24

Keywords

  • Influenza A virus
  • NS2
  • deubiquitinase
  • OTUB1

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