Molecular and Functional Dissection of the Human Antibody to the Epitope of Sars-Cov-2 Spike( I )

  • Huang, Kuan-Ying Arthur (PI)
  • Ma, Che Alex (CoPI)

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本計畫將促進了解人類抗新型冠狀病毒抗體免疫在血清與抗體株譜層次的內容,評估抗體免疫與病毒抗原性演變的互動,以及確立臨床前抗體藥物的組合與優化方向。我們預期這些結果對未來抗病毒藥物發展、疫苗反應評估、與疫苗抗原優化亦有相當重要性。

Project IDs

Project ID:PC11007-2681
External Project ID:MOST110-2628-B182-013
StatusFinished
Effective start/end date01/08/2131/07/22

Keywords

  • SARS-CoV-2 spike
  • Human antibody profiles
  • Epitope mapping
  • Antigenic variation
  • Potent human monoclonal antibody
  • Preclinical development

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