Nanocatalytic and Photothermal Nanocomposites for Synergistic Multimodal Cancer Therapy

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

本計畫開發具癌症光熱療法/化學動力療法/飢餓療法聯合治療能力的奈米複合物，整合了葡萄糖氧化酶、還原石墨烯量子點、和MnO2的奈米複合物可以實現生化/化學反應的循環，增強飢餓治療療效，利用rGQD高光熱轉換效率除可以近紅外進行光熱治療，並可提昇催化反應速率，結合針對腫瘤缺氧/弱酸微環境的化學動力治療。利用所開發功能性奈米複合物提供的多項優點，以標靶傳輸奈米複合物的給藥方式，結合有效近紅外光激發，可提供癌症多重治療平台，提升腫瘤治療成效。利用此功能化奈米複合物進行癌症治療，預期可提供創新具臨床應用潛力的癌症奈米醫學新療法。

Project IDs

Project ID:PC11207-2119
External Project ID:NSTC112-2314-B182-046-MY2
StatusFinished
Effective start/end date01/08/23 → 31/07/24

Keywords

  • Graphene quantum dot
  • photothermal therapy
  • chemodynamic therapy
  • starvation therapy
  • cancer combination therapy

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