Perinatal Exposure to Nanoplastics Can Lead to Lung Dysplasia in Infants through Nf-Κb Pathway and Placental Shaping and Its Prevention Strategy

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

周產期微塑料暴露是現代社會中日益嚴重影響後代健康的逆境。對於周產期微塑料暴露對後代的影響,我們所知很有限。這個知識差的填補正是我們後續管理微塑料暴露風險的基礎。就我們所知,這是第一個周產期微塑料暴露如何影響子代肺部的研究。通過這個研究,我們可以了解周產期微塑料暴露如何影響下一代的肺部健康。我們也有機會開發一種新策略來預防現代社會這個嚴重的母胎逆境。

Project IDs

Project ID:PC11207-2116
External Project ID:NSTC112-2314-B182-029-MY3
StatusFinished
Effective start/end date01/08/2331/07/24

Keywords

  • The origin of the development of health and disease (DOHaD)
  • perinatal period
  • exposure to nanoscale microplastics
  • placental remodeling
  • offspring
  • macrophages
  • NF-κB
  • lung development

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