Revitalizing Lymphatic Endothelial Cells (Lecs) by Adipose-Derived Stem Cells (Ascs) for Engineering Vascularized Lymphatic Tissue Engineering

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

源於癌症治療的淋巴水腫,帶來病患生活品質的改變,也引發龐大的相關醫療支出,尋求有效治療方式,是組織工程領域的挑戰。但若能藉由組織工程的方式發展可能的治療方式,將是一大突破。運用帶血管的動物模組的甚少,放射線治療後的淋巴上皮細胞的運用也極少,然而,相關知識的累積將有助於運用組織工程方式於淋巴結廓清與放射線治療處(亦即淋巴管被破壞之處),直接修復。本計畫的設計獨特,將累積相關知識,提供損傷淋巴組織修復方式,極具臨床運用的機會與價值的。另外,淋巴組織工程相關知識基礎,也讓再生醫學運用於癌症研究與癌症藥物投予更具可行性。

Project IDs

Project ID:PC11307-1383
External Project ID:NSTC113-2314-B182-024-MY3
StatusActive
Effective start/end date01/08/2431/07/25

Keywords

  • Tissue engineering
  • Lymph
  • Lymphatic
  • Lymphedema
  • LEC
  • ASC
  • Radiation

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