Revolutionizing Metabolic Imaging: Enhancing Hyperpolarized Carbon-13 Mri with Advanced Ideal Csi Modeling

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

這份研究計劃書旨在提升超極化（HP）碳-13磁共振成像的IDEAL CSI模型。其目的是解決數據分析和重建中的挑戰，特別是針對如乳酸等下游代謝物信號的快速衰減和影像假影問題。提出的方法僅需一個數據集即可估算代謝轉換，預期將提供更準確的代謝比率和交換率計算。這項研究有潛力將HP 13C MRI的定性特徵轉換為定量數據，深入洞察疾病進展。這種創新方法對臨床研究具有重要意義，因為它能提高癌症和其他疾病治療反應及診斷代謝成像的可靠性。該研究與當前代謝成像的發展趨勢相符，有望為該領域貢獻寶貴的知識。

Project IDs

Project ID:PB11307-2729
External Project ID:NSTC113-2221-E182-026
StatusActive
Effective start/end date01/08/24 → 31/07/25

Keywords

  • Hyperpolarized Carbon-13 MRI
  • Pyruvate
  • Apparent Exchange Rate Constant
  • IDEAL Spiral CSI Sequence and Reconstruction

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