Role of Core Fucosylation of Secreted Protein Acidic and Rich in Cysteine (Sparc) in Chronic Obstructive Pulmonary Disease (Copd): Impact of Hypoxia and Polycyclic Aromatic Hydrocarbons

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

目前對COPD的機轉仍然不詳，我們若能找到一個有效的偵測因子，如：SPARC、core-fucosylated SPARC，我們將可清楚病人的疾病進展和相關環境因子對疾病的影響，將來有機會發展成疾病治療的標的，減少COPD患者會社會經濟的負擔；如果我們的研究成功將可提升台灣在國際COPD研究領域的地位。

Project IDs

Project ID:PC11208-0036
External Project ID:NSTC111-2314-B182-051-MY3
StatusFinished
Effective start/end date01/08/23 → 31/07/24

Keywords

  • Chronic obstructive pulmonary disease
  • Secreted protein acidic and rich in cysteine
  • Core fucosylation
  • Fibrocytes
  • Polycyclic aromatic hydrocarbons
  • Hypoxia

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