Project Details
Abstract
Hepatocellular carcinoma (HCC) is the number one of the ten leading cancer death in Taiwan and has
been picked up as the target diseases by NRPGM. We have proposed and organized an HCC research
network that could coordinate the major medical centers in Taiwan to conduct a prospective study.
This network (Taiwan Liver Cancer Network, TLCN) currently includes five major medical centers in
northern, central, and southern parts of Taiwan (NTUH, CGMH-Linko, VGH-Taichung, CGMH-Kaohsiung,
VGH-Kaohsiung) to conduct a prospective study, so that we will be able to collect HCC patients with
various socioeconomic, ethnical and life style backgrounds as well as regional representativeness.
The resected HCC and non-tumor tissues will be separated and snap-frozen at each collaborating
hospital and periodically shipped to the central tissue bank at NHRI, Zhunan. Other biosamples,
such as serum, plasma and blood cells will be stored in the tissue bank, too. Up to now, we have
collected 6,500 liver cancer patients with tissue or blood samples and sufficient clinical
pathological and virological information. This network has started to accept applications for
biosamples from individual PI in Taiwan since 2007, including DNA, RNA, tissue sections and tissue
fragment for protein extraction. So far, we already have 71 applicants, all of them are professors
from national universities and medical centers. Up to now, we have sent out more than 25,000
biospecimens and their clinical data. We also have built up follow up data of the initial 3 year’s
patients by the end of 2012. Twenty-two blocks of HCC tissue arrays of various groups of HCC
patients and 6 blocks of cholangiocarcinoma tissue arrays with 37 tumor and paired non-tumor
tissues were also made, and ready for application. After the clinical and follow up database is
well organized, our HCC network should be one of the largest and best HCC patient database and
tissue bank in the world.
Project IDs
Project ID:PC10206-0165
External Project ID:NSC102-2325-B182-018
External Project ID:NSC102-2325-B182-018
Status | Finished |
---|---|
Effective start/end date | 01/05/13 → 30/04/14 |
Keywords
- hepatocellular carcinoma
- HCC
- tissue bank
- network
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