Study of Polyelectrolyte Multilayer Modified Epoxidized Styrene-Butadiene-Styrene Copolymer for Biomaterials

  • Yang, Jen-Ming (PI)

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

First Year: To enhance the functional activity, epoxidized styrene-butadiene-styrene block copolymer will be modified to get the carboxylated SBS. The performance of modified SBS will also be studied for the application for wound dressing. Second Year: Combining the techniques developed from the first year, the layer-by-layer multiple polyelectrolyte modified carboxylated styrene-butadiene-styrene copolymer will be prepared in this study. The polyelectrolyte multilayer will be prepared by using chitosan and lysine as polycation. Heparin, sodium alginate and polyglutarmic acid will be used as polyanion for this study. The optimum condition for the polyelectrolyte multilayer will also be studied. The performance of the membrane as biomaterials will be evaluated. Combining the photolithographic techniques and cell co-culture technique, the cell-substrate interaction will be evaluated. The effect of co-culture and pattern of polyelectrolyte multilayer on the cell interaction will also be evaluated.

Project IDs

Project ID:PB9902-1050
External Project ID:NSC98-2221-E182-002-MY2
StatusFinished
Effective start/end date01/08/1031/07/11

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.