Study of the Coordinated Assembly of Kshv Lytic Dna Replication Proteins

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

卡波西氏肉瘤病毒是一個重要的致癌病毒。由於病毒溶裂生活史, 是致癌機轉重要的一環, 我們深信若能充分了解這些病毒核心複製蛋白質的協調性組裝, 此不僅能提供對病毒複製機制的深入認識, 此也有利於未來發展疾病治療的新策略。

Project IDs

Project ID:PC11107-4585
External Project ID:MOST109-2320-B182-027-MY3
StatusFinished
Effective start/end date01/08/2231/07/23

Keywords

  • Kaposi’s sarcoma-associated herpesvirus
  • Lytic DNA replication
  • Primase
  • Helicase
  • DNA polymerase
  • Cytoplasmic retention
  • Nuclear export control
  • Protein stability

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